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Pard3b Gene Detail
Summary
  • Symbol
    Pard3b
  • Name
    par-3 family cell polarity regulator beta
  • Synonyms
    1810008K04Rik, 2010002N16Rik, 2810455B10Rik, Als2cr19, PAR3B, PAR3beta, PAR3L
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919301
    NCBI Gene: 72823
  • Alliance
    genome feature page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:61677983-62681443 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 30.92 cM, cytoband C2
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    19930 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919301
 protein coding gene Chr1:61677825-62681443 (+)
129S1/SvImJ ENSMUSG00200018276
 protein coding gene Chr1:59182835-60194713 (+)
A/J ENSMUSG00195028573
 protein coding gene Chr1:58711786-59716329 (+)
AKR/J ENSMUSG00220040057
 protein coding gene Chr1:58837524-59839081 (+)
BALB/cJ ENSMUSG00180013213
 protein coding gene Chr1:59002237-60005026 (+)
C3H/HeJ ENSMUSG00175000817
 protein coding gene Chr1:59101378-60105824 (+)
C57BL/6NJ ENSMUSG00215030249
 protein coding gene Chr1:59026861-60030826 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014194
 protein coding gene Chr1:55712872-56678511 (+)
CAST/EiJ ENSTCUG00005012895
 protein coding gene Chr1:58848213-59871376 (+)
CBA/J ENSMUSG00210032388
 protein coding gene Chr1:58780620-59786942 (+)
DBA/2J ENSMUSG00185038681
 protein coding gene Chr1:59899273-60903770 (+)
FVB/NJ ENSMUSG00205013586
 protein coding gene Chr1:58732661-59739971 (+)
JF1/MsJ ENSUMUG00000034436
 protein coding gene Chr1:58829910-59843824 (+)
LP/J ENSMUSG00230028320
 protein coding gene Chr1:59899848-60904257 (+)
NOD/ShiLtJ ENSMUSG00190032014
 protein coding gene Chr1:58969810-59970957 (+)
NZO/HlLtJ ENSMUSG00225000988
 protein coding gene Chr1:63124411-64128848 (+)
PWK/PhJ ENSLUMG00010025057
 protein coding gene Chr1:58359732-59361976 (+)
SPRET/EiJ ENSMSPG00010025603
 protein coding gene Chr1:60343733-61378417 (+)
WSB/EiJ ENSIUOG00005018032
 protein coding gene Chr1:58567702-59579190 (+)



Homology
more
  • Human Ortholog
    PARD3B, par-3 family cell polarity regulator beta
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PARD3B, par-3 family cell polarity regulator beta
  • Synonyms
    ALS2CR19, PAR3B, PAR3beta, PAR3L
  • Links
    NCBI Gene ID: 117583
    UniProt: Q8TEW8

  • Chr Location
    2q33.3; chr2:204545475-205620162 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    687
  • Tissues
    19
  • cDNA Data
    11
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000052062 Ensembl Gene Model | MGI Sequence Detail 1003461 C57BL/6J ±  kb
    transcript ENSMUST00000075374 Ensembl | MGI Sequence Detail 8392 Not Applicable  
    polypeptide ENSMUSP00000074837 Ensembl | MGI Sequence Detail 1203 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 12
      Genomic 1
      cDNA 11

      Microarray probesets 8
    Other
    Accession IDs
    less
    MGI:1916317, MGI:1920073
    References
    more
    • Summaries
      All 50
      Developmental Gene Expression 4
      Gene Ontology 6
      Phenotypes 16
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:378324 Zhang W, et al., Polarity protein Par3L deletion causes chromosomal segregation defects and tumorigenesis. J Biol Chem. 2025 Nov 20;302(1):110966
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory