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Rchy1 Gene Detail
Summary
  • Symbol
    Rchy1
  • Name
    ring finger and CHY zinc finger domain containing 1
  • Synonyms
    6720407C15Rik, Pirh2, PRO1996, Zfp363
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915348
    NCBI Gene: 68098
  • Alliance
    genome feature page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:92096763-92110927 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 45.58 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    408 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915348
 protein coding gene Chr5:92096701-92110988 (-)
129S1/SvImJ ENSMUSG00200007463
 protein coding gene Chr5:87820659-87854349 (-)
A/J ENSMUSG00195024196
 protein coding gene Chr5:86970472-87012218 (-)
AKR/J ENSMUSG00220011267
 protein coding gene Chr5:87123062-87159207 (-)
BALB/cJ ENSMUSG00180021811
 protein coding gene Chr5:86817454-86853596 (-)
C3H/HeJ ENSMUSG00175037966
 protein coding gene Chr5:88918260-88954399 (-)
C57BL/6NJ ENSMUSG00215023692
 protein coding gene Chr5:87669599-87711340 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027405
 protein coding gene Chr5:85056555-85071671 (-)
CAST/EiJ ENSTCUG00005035247
 protein coding gene Chr5:86541817-86578279 (-)
CBA/J ENSMUSG00210005884
 protein coding gene Chr5:87697000-87733144 (-)
DBA/2J ENSMUSG00185037220
 protein coding gene Chr5:89633735-89669871 (-)
FVB/NJ ENSMUSG00205019925
 protein coding gene Chr5:86522429-86558568 (-)
JF1/MsJ ENSUMUG00000019660
 protein coding gene Chr5:93884263-93916773 (-)
LP/J ENSMUSG00230027511
 protein coding gene Chr5:94331856-94365545 (-)
NOD/ShiLtJ ENSMUSG00190028964
 protein coding gene Chr5:86599111-86640859 (-)
NZO/HlLtJ ENSMUSG00225008594
 protein coding gene Chr5:99470357-99512100 (-)
PWK/PhJ ENSLUMG00010025388
 protein coding gene Chr5:86568763-86604304 (-)
SPRET/EiJ ENSMSPG00010030839
 protein coding gene Chr5:88964392-88980634 (-)
WSB/EiJ ENSIUOG00005025343
 protein coding gene Chr5:89595732-89631877 (-)



Homology
more
  • Human Ortholog
    RCHY1, ring finger and CHY zinc finger domain containing 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RCHY1, ring finger and CHY zinc finger domain containing 1
  • Synonyms
    ARNIP, CHIMP, PIRH2, PRO1996, RNF199, ZCHY, ZNF363
  • Links
    NCBI Gene ID: 25898
    UniProt: Q96PM5

  • Chr Location
    4q21.1; chr4:75479033-75514764 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    15
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Gene trapped
    7
  • Radiation induced
    1
  • Spontaneous
    1
  • Targeted
    3
  • Genomic Mutations
    3 involving Rchy1
  • Incidental Mutations
    Mutagenetix , APF
  • Find Mice (IMSR)
    26 strains or lines available
Mouse embryonic fibroblasts from mice homozygous for a knock-out allele exhibit decreased cellular sensitivity to UV irradiation.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    52
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    10
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000029397 Ensembl Gene Model | MGI Sequence Detail 14165 C57BL/6J ±  kb
transcript ENSMUST00000031345 Ensembl | MGI Sequence Detail 1967 Not Applicable  
polypeptide ENSMUSP00000031345 Ensembl | MGI Sequence Detail 261 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 2
Other
Accession IDs
less
MGI:2141088
References
more
  • Summaries
    All 52
    Developmental Gene Expression 2
    Gene Ontology 10
    Phenotypes 16
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:380373 Bridoux L, et al., Molecular Analysis of the HOXA2-Dependent Degradation of RCHY1. PLoS One. 2015;10(10):e0141347
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory