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Atp5mc2 Gene Detail
Summary
  • Symbol
    Atp5mc2
  • Name
    ATP synthase membrane subunit c locus 2
  • Synonyms
    1810041M08Rik, Atp5g2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915192
    NCBI Gene: 67942
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:102571303-102579482 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 57.77 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    260 from dbSNP Build 142
  • Strain Annotations
    22
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915192
 protein coding gene Chr15:102571299-102580787 (-)
129S1/SvImJ ENSMUSG00200050111
 protein coding gene Chr15:99796237-99805725 (-)
A/J ENSMUSG00195042987
 protein coding gene Chr15:99685306-99694798 (-)
AKR/J ENSMUSG00220047732
 protein coding gene Chr7:28302797-28303458 (+)
AKR/J ENSMUSG00220046806
 protein coding gene Chr15:99655317-99664809 (-)
BALB/cJ ENSMUSG00180039438
 protein coding gene Chr15:99568865-99578353 (-)
C3H/HeJ ENSMUSG00175034679
 protein coding gene Chr15:99887133-99896624 (-)
C57BL/6NJ ENSMUSG00215050156
 protein coding gene Chr15:99612312-99621800 (-)
C57BL/6NJ ENSMUSG00215054685
 protein coding gene Chr7:13561569-13562320 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020360
 protein coding gene Chr15:96505940-96515639 (-)
CAST/EiJ ENSTCUG00005041950
 protein coding gene Chr15:99085156-99094785 (-)
CBA/J ENSMUSG00210028501
 protein coding gene Chr15:99638328-99647820 (-)
DBA/2J ENSMUSG00185051826
 protein coding gene Chr7:17593558-17594257 (-)
DBA/2J ENSMUSG00185037005
 protein coding gene Chr15:99655135-99664627 (-)
FVB/NJ ENSMUSG00205044743
 protein coding gene Chr7:14395128-14395827 (-)
FVB/NJ ENSMUSG00205039276
 protein coding gene Chr15:99359894-99369385 (-)
JF1/MsJ no annotation
LP/J ENSMUSG00230005805
 protein coding gene Chr15:103017242-103026730 (-)
NOD/ShiLtJ ENSMUSG00190035046
 protein coding gene Chr15:99599977-99609469 (-)
NZO/HlLtJ ENSMUSG00225024707
 protein coding gene Chr7:21535404-21536103 (-)
NZO/HlLtJ ENSMUSG00225027931
 protein coding gene Chr15:103196827-103206317 (-)
PWK/PhJ ENSLUMG00010048974
 protein coding gene Chr15:99324272-99333767 (-)
SPRET/EiJ no annotation
WSB/EiJ ENSIUOG00005035377
 protein coding gene Chr15:99739524-99749012 (-)



Homology
more
  • Human Ortholog
    ATP5MC2, ATP synthase membrane subunit c locus 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ATP5MC2, ATP synthase membrane subunit c locus 2
  • Synonyms
    ATP5A, ATP5G2
  • Links
    NCBI Gene ID: 517
    UniProt: Q06055

  • Chr Location
    12q13.13; chr12:53632726-53681423 (-)  GRCh38
Human Diseases
more
  • Diseases
    2 with human ATP5MC2 associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    32 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    694
  • Tissues
    95
  • cDNA Data
    6
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 67942 NCBI Gene Model | MGI Sequence Detail 8180 C57BL/6J ±  kb
    transcript NM_026468 RefSeq | MGI Sequence Detail 647 C57BL/6  
    polypeptide P56383 UniProt | EBI | MGI Sequence Detail 146 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      3 Sequences
    • Protein Ontology
      PR:000030948 ATP synthase F(0) complex subunit C2, mitochondrial
      (term hierarchy)
    • InterPro Domains
      IPR000454 ATP synthase, F0 complex, subunit C
      IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site
      IPR038662 F1F0 ATP synthase subunit C superfamily
      IPR035921 F/V-ATP synthase subunit C superfamily
      IPR002379 V-ATPase proteolipid subunit C-like domain
    • GlyGen
      P56383 1 site, 1 O-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 6
      cDNA 6
      Antibodies 1

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:7469638
    References
    more
    • Summaries
      All 57
      Developmental Gene Expression 2
      Diseases 1
      Gene Ontology 6
      Phenotypes 32
    • Earliest
      J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
    • Latest
      J:387680 Ahn B, et al., Disorganization of Transcriptional Regulation and Alteration of Keratin Family Gene Expression in Hairy Ear Mice. Genes (Basel). 2026 Jan 31;17(2)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory