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Zfp639 Gene Detail
Summary
  • Symbol
    Zfp639
  • Name
    zinc finger protein 639
  • Synonyms
    6230400O18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915028
    NCBI Gene: 67778
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:32564408-32574982 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 15.75 cM, cytoband B
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    318 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915028
 protein coding gene Chr3:32564355-32574982 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027138
 protein coding gene Chr3:30122273-30136696 (+)
A/J MGP_AJ_G0027098
 protein coding gene Chr3:29695711-29706289 (+)
AKR/J MGP_AKRJ_G0027067
 protein coding gene Chr3:30154833-30165411 (+)
BALB/cJ MGP_BALBcJ_G0027110
 protein coding gene Chr3:29344408-29354982 (+)
C3H/HeJ MGP_C3HHeJ_G0026853
 protein coding gene Chr3:30176257-30187595 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027556
 protein coding gene Chr3:31618865-31629439 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024917
 protein coding gene Chr3:27523718-27534466 (+)
CAST/EiJ MGP_CASTEiJ_G0026306
 protein coding gene Chr3:30042076-30052830 (+)
CBA/J MGP_CBAJ_G0026830
 protein coding gene Chr3:32462874-32476984 (+)
DBA/2J MGP_DBA2J_G0026964
 protein coding gene Chr3:29164514-29175092 (+)
FVB/NJ MGP_FVBNJ_G0026932
 protein coding gene Chr3:28624615-28635193 (+)
LP/J MGP_LPJ_G0027076
 protein coding gene Chr3:30887529-30898107 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026952
 protein coding gene Chr3:34974977-34985444 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027615
 protein coding gene Chr3:29948027-29958603 (+)
PWK/PhJ MGP_PWKPhJ_G0026039
 protein coding gene Chr3:28706694-28717471 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025851
 protein coding gene Chr3:29351885-29362425 (+)
WSB/EiJ MGP_WSBEiJ_G0026380
 protein coding gene Chr3:29958563-29969137 (+)



Homology
more
  • Human Ortholog
    ZNF639, zinc finger protein 639
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF639, zinc finger protein 639
  • Synonyms
    ANC-2H01, ANC_2H01, ZASC1
  • Links
    NCBI Gene ID: 51193
    neXtProt AC: NX_Q9UID6
    UniProt: Q9UID6

  • Chr Location
    3q26.33; chr3:179322876-179338583 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous knockout reduces susceptibility to retrovirus infection but does not affect the infection-related tumor susceptibility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    29
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    768
  • Tissues
    52
  • cDNA Data
    69
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000027667 Ensembl Gene Model | MGI Sequence Detail 10575 C57BL/6J ±  kb
transcript ENSMUST00000029203 Ensembl | MGI Sequence Detail 1458 Not Applicable  
polypeptide ENSMUSP00000029203 Ensembl | MGI Sequence Detail 485 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 71
    cDNA 70
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 34
    Developmental Gene Expression 5
    Diseases 1
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/22/2024
MGI 6.24 		The Jackson Laboratory