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Prpsap1 Gene Detail
Summary
  • Symbol
    Prpsap1
  • Name
    phosphoribosyl pyrophosphate synthetase-associated protein 1
  • Synonyms
    5730409F23Rik, PAP39
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915013
    NCBI Gene: 67763
  • Alliance
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:116361671-116385461 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 11, 81.34 cM, cytoband E2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    834 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915013
protein coding gene Chr11:116361641-116385739 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019429
protein coding gene Chr11:120586844-120617591 (-)
A/J MGP_AJ_G0019397
protein coding gene Chr11:115314088-115341048 (-)
AKR/J MGP_AKRJ_G0019368
protein coding gene Chr11:118752220-118778197 (-)
BALB/cJ MGP_BALBcJ_G0019372
protein coding gene Chr11:115720255-115744416 (-)
C3H/HeJ MGP_C3HHeJ_G0019178
protein coding gene Chr11:119108744-119133234 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019821
protein coding gene Chr11:124279658-124304133 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017445
protein coding gene Chr11:112320818-112347414 (-)
CAST/EiJ MGP_CASTEiJ_G0018733
protein coding gene Chr11:120473596-120504936 (-)
CBA/J MGP_CBAJ_G0019149
protein coding gene Chr11:129197819-129223574 (-)
DBA/2J MGP_DBA2J_G0019261
protein coding gene Chr11:114748067-114772285 (-)
FVB/NJ MGP_FVBNJ_G0019253
protein coding gene Chr11:114254475-114277590 (-)
LP/J MGP_LPJ_G0019331
protein coding gene Chr11:120975265-121003456 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019286
protein coding gene Chr11:128244803-128272310 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019860
protein coding gene Chr11:119407961-119438874 (-)
PWK/PhJ MGP_PWKPhJ_G0018497
protein coding gene Chr11:116069665-116094240 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018290
protein coding gene Chr11:119161756-119189140 (-)
WSB/EiJ MGP_WSBEiJ_G0018785
protein coding gene Chr11:119377618-119405644 (-)



Homology
more
  • Human Ortholog
    PRPSAP1, phosphoribosyl pyrophosphate synthetase associated protein 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PRPSAP1, phosphoribosyl pyrophosphate synthetase associated protein 1
  • Synonyms
    PAP39
  • Links
    NCBI Gene ID: 5635
    neXtProt AC: NX_Q14558
    UniProt: Q14558

  • Chr Location
    17q25.1; chr17:76309478-76384521 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000015869 Ensembl Gene Model | MGI Sequence Detail 23791 C57BL/6J ±  kb
transcript ENSMUST00000106391 Ensembl | MGI Sequence Detail 1841 Not Applicable  
polypeptide ENSMUSP00000101999 Ensembl | MGI Sequence Detail 385 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000013294 phosphoribosyl pyrophosphate synthase-associated protein 1
  • InterPro Domains
    IPR000836 Phosphoribosyltransferase domain
    IPR029057 Phosphoribosyltransferase-like
    IPR005946 Ribose-phosphate pyrophosphokinase
    IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain
  • GlyGen
    Q9D0M1 3 sites, 2 N-linked glycans (2 sites), 1 O-linked glycan (1 site)
Molecular
Reagents
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  • All nucleic 119
    Genomic 1
    cDNA 118

    Microarray probesets 4
References
more
  • Summaries
    All 33
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
  • Latest
    J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory