About   Help   FAQ
Fam174a Gene Detail
Summary
  • Symbol
    Fam174a
  • Name
    family with sequence similarity 174, member A
  • Synonyms
    2310044D20Rik, Tmem157
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914948
    NCBI Gene: 67698
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:95241353-95263009 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 47.76 cM, cytoband D
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    731 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914948
 protein coding gene Chr1:95241348-95263009 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016354
 protein coding gene Chr1:97011510-97033166 (+)
A/J MGP_AJ_G0016338
 protein coding gene Chr1:93551046-93572708 (+)
AKR/J MGP_AKRJ_G0016299
 protein coding gene Chr1:96294585-96316246 (+)
BALB/cJ MGP_BALBcJ_G0016294
 protein coding gene Chr1:93742097-93763753 (+)
C3H/HeJ MGP_C3HHeJ_G0016120
 protein coding gene Chr1:96564352-96586014 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016753
 protein coding gene Chr1:100827565-100850130 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014471
 protein coding gene Chr1:88078268-88100016 (+)
CAST/EiJ MGP_CASTEiJ_G0015703
 protein coding gene Chr1:95875726-95898947 (+)
CBA/J MGP_CBAJ_G0016094
 protein coding gene Chr1:104072079-104095010 (+)
DBA/2J MGP_DBA2J_G0016199
 protein coding gene Chr1:92776587-92800237 (+)
FVB/NJ MGP_FVBNJ_G0016200
 protein coding gene Chr1:91827923-91849584 (+)
LP/J MGP_LPJ_G0016273
 protein coding gene Chr1:98262595-98284253 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016226
 protein coding gene Chr1:107335729-107360851 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016792
 protein coding gene Chr1:96322257-96343916 (+)
PWK/PhJ MGP_PWKPhJ_G0015491
 protein coding gene Chr1:92076259-92098054 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015275
 protein coding gene Chr1:95195225-95218995 (+)
WSB/EiJ MGP_WSBEiJ_G0015766
 protein coding gene Chr1:96143494-96165160 (+)



Homology
more
  • Human Ortholog
    FAM174A, family with sequence similarity 174 member A
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM174A, family with sequence similarity 174 member A
  • Synonyms
    HGS_RE408, NS5ATP6, TMEM157, UNQ1912
  • Links
    NCBI Gene ID: 345757
    UniProt: Q8TBP5

  • Chr Location
    5q21.1; chr5:100535338-100586741 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    3
  • Gene trapped
    1
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Fam174a
  • Find Mice (IMSR)
    12 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    27
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 67698 NCBI Gene Model | MGI Sequence Detail 21657 C57BL/6J ±  kb
transcript NM_026321 RefSeq | MGI Sequence Detail 2107 C57BL/6  
polypeptide Q9D3L0 UniProt | EBI | MGI Sequence Detail 190 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 29
    cDNA 29

    Microarray probesets 4
References
more
  • Summaries
    All 30
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
10/07/2025
MGI 6.24 		The Jackson Laboratory