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Aagab Gene Detail
Summary
  • Symbol
    Aagab
  • Name
    alpha- and gamma-adaptin binding protein
  • Synonyms
    2310007F21Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914189
    NCBI Gene: 66939
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:63509942-63551870 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 34.19 cM, cytoband D
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    224 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914189
 protein coding gene Chr9:63509897-63551872 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034931
 protein coding gene Chr9:63214290-63253183 (+)
A/J MGP_AJ_G0034911
 protein coding gene Chr9:61110295-61149513 (+)
AKR/J MGP_AKRJ_G0034841
 protein coding gene Chr9:62529274-62569742 (+)
BALB/cJ MGP_BALBcJ_G0034904
 protein coding gene Chr9:60837619-60876745 (+)
C3H/HeJ MGP_C3HHeJ_G0034614
 protein coding gene Chr9:63050293-63089633 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035423
 protein coding gene Chr9:64933325-64972073 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032334
 protein coding gene Chr9:60771331-60810127 (+)
CAST/EiJ MGP_CASTEiJ_G0033935
 protein coding gene Chr9:63201388-63242414 (+)
CBA/J MGP_CBAJ_G0034585
 protein coding gene Chr9:67178574-67217573 (+)
DBA/2J MGP_DBA2J_G0034744
 protein coding gene Chr9:60896654-60935312 (+)
FVB/NJ MGP_FVBNJ_G0034686
 protein coding gene Chr9:60195607-60235510 (+)
LP/J MGP_LPJ_G0034827
 protein coding gene Chr9:63503336-63542442 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034729
 protein coding gene Chr9:68501544-68541787 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035445
 protein coding gene Chr9:62628044-62668398 (+)
PWK/PhJ MGP_PWKPhJ_G0033639
 protein coding gene Chr9:61040851-61080629 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033473
 protein coding gene Chr9:62896580-62936064 (+)
WSB/EiJ MGP_WSBEiJ_G0034048
 protein coding gene Chr9:62524818-62565440 (+)



Homology
more
  • Human Ortholog
    AAGAB, alpha and gamma adaptin binding protein
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    AAGAB, alpha and gamma adaptin binding protein
  • Synonyms
    KPPP1, p34, PPKP1, PPKP1A
  • Links
    NCBI Gene ID: 79719
    neXtProt AC: NX_Q6PD74
    UniProt: Q6PD74

  • Chr Location
    15q23; chr15:67200667-67255198 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human AAGAB associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    736
  • Tissues
    3
  • cDNA Data
    76
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037257 Ensembl Gene Model | MGI Sequence Detail 41929 C57BL/6J ±  kb
transcript ENSMUST00000041551 Ensembl | MGI Sequence Detail 5294 Not Applicable  
polypeptide ENSMUSP00000048595 Ensembl | MGI Sequence Detail 316 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 76
    cDNA 76

    Microarray probesets 2
References
more
  • Summaries
    All 30
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory