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Rnpepl1 Gene Detail
Summary
  • Symbol
    Rnpepl1
  • Name
    arginyl aminopeptidase (aminopeptidase B)-like 1
  • Synonyms
    1110014H17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914170
    NCBI Gene: 108657
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:92837697-92848307 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 46.60 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    295 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914170
 protein coding gene Chr1:92837697-92852106 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016329
 protein coding gene Chr1:94516020-94531319 (+)
A/J MGP_AJ_G0016310
 protein coding gene Chr1:91130778-91144379 (+)
AKR/J MGP_AKRJ_G0016271
 protein coding gene Chr1:93820678-93834279 (+)
BALB/cJ MGP_BALBcJ_G0016266
 protein coding gene Chr1:91301458-91315059 (+)
C3H/HeJ MGP_C3HHeJ_G0016095
 protein coding gene Chr1:94071209-94084799 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016725
 protein coding gene Chr1:98111972-98125578 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014443
 protein coding gene Chr1:85378308-85391921 (+)
CAST/EiJ MGP_CASTEiJ_G0015678
 protein coding gene Chr1:93394653-93412091 (+)
CBA/J MGP_CBAJ_G0016069
 protein coding gene Chr1:101283378-101296968 (+)
DBA/2J MGP_DBA2J_G0016174
 protein coding gene Chr1:90327451-90341113 (+)
FVB/NJ MGP_FVBNJ_G0016173
 protein coding gene Chr1:89395319-89408926 (+)
LP/J MGP_LPJ_G0016245
 protein coding gene Chr1:95698504-95712121 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016198
 protein coding gene Chr1:104416659-104430260 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016764
 protein coding gene Chr1:93843101-93856697 (+)
PWK/PhJ MGP_PWKPhJ_G0015463
 protein coding gene Chr1:89761169-89776858 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015247
 protein coding gene Chr1:92782088-92797654 (+)
WSB/EiJ MGP_WSBEiJ_G0015738
 protein coding gene Chr1:93649086-93662718 (+)



Homology
more
  • Human Ortholog
    RNPEPL1, arginyl aminopeptidase like 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RNPEPL1, arginyl aminopeptidase like 1
  • Links
    NCBI Gene ID: 57140
    neXtProt AC: NX_Q9HAU8
    UniProt: Q9HAU8

  • Chr Location
    2q37.3; chr2:240565804-240581372 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    749
  • Tissues
    29
  • cDNA Data
    97
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 108657 NCBI Gene Model | MGI Sequence Detail 10611 C57BL/6J ±  kb
    transcript NM_181405 RefSeq | MGI Sequence Detail 3056 C57BL/6  
    polypeptide G5E872 UniProt | EBI | MGI Sequence Detail 720 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      7 Sequences
    • Protein Ontology
      PR:000014148 aminopeptidase RNPEPL1
      (term hierarchy)
    • EC
      3.4.11.-, 3.4.11.18
    • InterPro Domains
      IPR034015 Aminopeptidase, leukotriene A4 hydrolase-like
      IPR045357 Aminopeptidase N-like , N-terminal domain
      IPR042097 Aminopeptidase N-like , N-terminal domain superfamliy
      IPR016024 Armadillo-type fold
      IPR049980 Leukotriene A4 hydrolase-like, catalytic domain
      IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase
      IPR015211 Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal
      IPR038502 Peptidase M1, LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily
      IPR014782 Peptidase M1, membrane alanine aminopeptidase
      IPR027268 Peptidase M4/M1, CTD superfamily
    Molecular
    Reagents
    less
    • All nucleic 97
      cDNA 97

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2138375
    References
    more
    • Summaries
      All 34
      Developmental Gene Expression 1
      Gene Ontology 5
      Phenotypes 7
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    10/22/2024
    MGI 6.24     		The Jackson Laboratory