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Crebl2 Gene Detail
Summary
  • Symbol
    Crebl2
  • Name
    cAMP responsive element binding protein-like 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1889385
    NCBI Gene: 232430
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:134807117-134835894 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 65.77 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    677 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1889385
 protein coding gene Chr6:134807090-134835894 (+)
129S1/SvImJ ENSMUSG00200044434
 protein coding gene Chr6:132305085-132332829 (+)
A/J ENSMUSG00195031236
 protein coding gene Chr6:131163915-131192621 (+)
AKR/J ENSMUSG00220033305
 protein coding gene Chr6:129388330-129417037 (+)
BALB/cJ ENSMUSG00180035872
 protein coding gene Chr6:131236219-131264922 (+)
C3H/HeJ ENSMUSG00175034136
 protein coding gene Chr6:131184300-131213001 (+)
C57BL/6NJ ENSMUSG00215027165
 protein coding gene Chr6:131426850-131455632 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028982
 protein coding gene Chr6:132806276-132836722 (+)
CAST/EiJ ENSTCUG00005037123
 protein coding gene Chr6:132091254-132119940 (+)
CBA/J ENSMUSG00210015930
 protein coding gene Chr6:131202732-131231431 (+)
DBA/2J ENSMUSG00185021769
 protein coding gene Chr6:131898944-131927641 (+)
FVB/NJ ENSMUSG00205030694
 protein coding gene Chr6:130327899-130356597 (+)
JF1/MsJ ENSUMUG00000029765
 protein coding gene Chr6:130643015-130671808 (+)
LP/J ENSMUSG00230006721
 protein coding gene Chr6:133100833-133155921 (+)
NOD/ShiLtJ ENSMUSG00190035419
 protein coding gene Chr6:131737186-131765890 (+)
NZO/HlLtJ ENSMUSG00225007553
 protein coding gene Chr6:135955978-135985222 (+)
PWK/PhJ ENSLUMG00010035630
 protein coding gene Chr6:129696070-129724790 (+)
SPRET/EiJ ENSMSPG00010030161
 protein coding gene Chr6:133493098-133521513 (+)
WSB/EiJ ENSIUOG00005041468
 protein coding gene Chr6:131998475-132027175 (+)



Homology
more
  • Human Ortholog
    CREBL2, cAMP responsive element binding protein like 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CREBL2, cAMP responsive element binding protein like 2
  • Links
    NCBI Gene ID: 1389
    UniProt: O60519

  • Chr Location
    12p13.1; chr12:12611827-12645108 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    691
  • Tissues
    94
  • cDNA Data
    8
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032652 Ensembl Gene Model | MGI Sequence Detail 28778 C57BL/6J ±  kb
transcript ENSMUST00000046303 Ensembl | MGI Sequence Detail 3629 Not Applicable  
polypeptide ENSMUSP00000035304 Ensembl | MGI Sequence Detail 123 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 5
References
more
  • Summaries
    All 32
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 9
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory