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Slc25a14 Gene Detail
Summary
  • Symbol
    Slc25a14
  • Name
    solute carrier family 25 (mitochondrial carrier, brain), member 14
  • Synonyms
    BMCP1, UCP5, UCP5L, UCP5S
  • Feature Type
    protein coding gene
  • IDs
    MGI:1330823
    NCBI Gene: 20523
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:47712333-47751171 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 25.69 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    997 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1330823
 protein coding gene ChrX:47712290-47751171 (+)
129S1/SvImJ ENSMUSG00200037646
 protein coding gene ChrX:31749838-31788971 (+)
A/J ENSMUSG00195016967
 protein coding gene ChrX:34351504-34390630 (+)
AKR/J ENSMUSG00220035807
 protein coding gene ChrX:31239914-31279041 (+)
BALB/cJ ENSMUSG00180031008
 protein coding gene ChrX:32081394-32120525 (+)
C3H/HeJ ENSMUSG00175038406
 protein coding gene ChrX:35100031-35139159 (+)
C57BL/6NJ ENSMUSG00215046998
 protein coding gene ChrX:32087209-32126497 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033046
 protein coding gene ChrX:41328206-41368204 (+)
CAST/EiJ no annotation
CBA/J ENSMUSG00210037993
 protein coding gene ChrX:32343549-32382677 (+)
DBA/2J ENSMUSG00185033168
 protein coding gene ChrX:43049946-43089073 (+)
FVB/NJ ENSMUSG00205020741
 protein coding gene ChrX:31029200-31069339 (+)
JF1/MsJ ENSUMUG00000022854
 protein coding gene ChrX:62097465-62136712 (+)
LP/J ENSMUSG00230019056
 protein coding gene ChrX:49582257-49621388 (+)
NOD/ShiLtJ ENSMUSG00190030973
 protein coding gene ChrX:31519177-31558298 (+)
NZO/HlLtJ ENSMUSG00225042797
 protein coding gene ChrX:54775913-54815036 (+)
PWK/PhJ ENSLUMG00010037224
 protein coding gene ChrX:31814820-31854085 (+)
SPRET/EiJ ENSMSPG00010024045
 protein coding gene ChrX:33400891-33446363 (+)
WSB/EiJ ENSIUOG00005045849
 protein coding gene ChrX:32623337-32662599 (+)



Homology
more
  • Human Ortholog
    SLC25A14, solute carrier family 25 member 14
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC25A14, solute carrier family 25 member 14
  • Synonyms
    BMCP1, UCP5
  • Links
    NCBI Gene ID: 9016
    UniProt: O95258

  • Chr Location
    Xq26.1; chrX:130339888-130373361 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    24
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    696
  • Tissues
    13
  • cDNA Data
    30
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 20523 NCBI Gene Model | MGI Sequence Detail 38839 C57BL/6J ±  kb
transcript NM_001403261 RefSeq | MGI Sequence Detail 1819 ZRU/MplStud  
polypeptide Q9Z2B2 UniProt | EBI | MGI Sequence Detail 325 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000015009 brain mitochondrial carrier protein 1
    (term hierarchy)
  • InterPro Domains
    IPR002067 Mitochondrial carrier protein
    IPR023395 Mitochondrial carrier protein domain superfamily
    IPR018108 Mitochondrial carrier protein, transmembrane region
    IPR050391 Mitochondrial Metabolite Transporter
Molecular
Reagents
less
  • All nucleic 34
    cDNA 31
    Primer pair 3

    Microarray probesets 3
Other
Accession IDs
less
MGI:1333769
References
more
  • Summaries
    All 43
    Developmental Gene Expression 4
    Gene Ontology 11
    Phenotypes 7
  • Earliest
    J:51513 Sanchis D, et al., BMCP1, a novel mitochondrial carrier with high expression in the central nervous system of humans and rodents, and respiration uncoupling activity in recombinant yeast. J Biol Chem. 1998 Dec 18;273(51):34611-5
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory