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Atp5po Gene Detail
Summary
  • Symbol
    Atp5po
  • Name
    ATP synthase peripheral stalk subunit OSCP
  • Synonyms
    Atp5o, D12Wsu28e
  • Feature Type
    protein coding gene
  • IDs
    MGI:106341
    NCBI Gene: 28080
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:91722111-91728518 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 53.26 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    371 from dbSNP Build 142
  • Strain Annotations
    31
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_106341
 protein coding gene Chr16:91481286-91728575 (-)
129S1/SvImJ ENSMUSGG00200054866
 protein coding gene Chr16:88651138-88652807 (-)
129S1/SvImJ ENSMUSG00200037787
 protein coding gene Chr16:88652684-88657243 (-)
A/J ENSMUSG00195026256
 protein coding gene Chr16:88409887-88414446 (-)
A/J ENSMUSG00195031926
 protein coding gene Chr3:53370692-53371439 (+)
A/J ENSMUSGG00195054986
 protein coding gene Chr16:88408341-88410010 (-)
AKR/J ENSMUSG00220029541
 protein coding gene Chr3:53431348-53432097 (+)
AKR/J ENSMUSG00220015144
 protein coding gene Chr16:88602875-88607436 (-)
AKR/J ENSMUSGG00220054800
 protein coding gene Chr16:88601329-88602998 (-)
BALB/cJ ENSMUSG00180014511
 protein coding gene Chr16:88483965-88488524 (-)
BALB/cJ ENSMUSGG00180055440
 protein coding gene Chr16:88482419-88484088 (-)
C3H/HeJ ENSMUSG00175013234
 protein coding gene Chr16:88821308-88825867 (-)
C3H/HeJ ENSMUSGG00175054779
 protein coding gene Chr16:88819762-88821431 (-)
C57BL/6NJ ENSMUSG00215029195
 protein coding gene Chr16:88612367-88616926 (-)
C57BL/6NJ ENSMUSGG00215055638
 protein coding gene Chr16:88610821-88612490 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020967
 protein coding gene Chr16:86075563-86323151 (-)
CAST/EiJ no annotation
CBA/J ENSMUSGG00210054508
 protein coding gene Chr16:88721023-88722706 (-)
CBA/J ENSMUSG00210037810
 protein coding gene Chr16:88722583-88727337 (-)
DBA/2J ENSMUSG00185031989
 protein coding gene Chr16:88671940-88676499 (-)
DBA/2J ENSMUSGG00185057655
 protein coding gene Chr16:88670394-88672063 (-)
FVB/NJ ENSMUSGG00205054297
 protein coding gene Chr16:88445454-88447123 (-)
FVB/NJ ENSMUSG00205013084
 protein coding gene Chr16:88447000-88451559 (-)
FVB/NJ ENSMUSG00205003276
 protein coding gene Chr3:52581423-52582175 (+)
JF1/MsJ no annotation
LP/J ENSMUSG00230032354
 protein coding gene Chr16:91199442-91204001 (-)
LP/J ENSMUSGG00230055571
 protein coding gene Chr16:91197896-91199565 (-)
NOD/ShiLtJ ENSMUSGG00190054755
 protein coding gene Chr16:88635661-88637330 (-)
NOD/ShiLtJ ENSMUSG00190026553
 protein coding gene Chr3:53779265-53780012 (+)
NOD/ShiLtJ ENSMUSG00190022838
 protein coding gene Chr16:88637207-88641768 (-)
NZO/HlLtJ ENSMUSG00225029997
 protein coding gene Chr16:94321980-94326539 (-)
NZO/HlLtJ ENSMUSGG00225055215
 protein coding gene Chr16:94320434-94322103 (-)
PWK/PhJ no annotation
SPRET/EiJ ENSMSPG00010027597
 protein coding gene Chr16:89577648-89584103 (-)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    ATP5PO, ATP synthase peripheral stalk subunit OSCP
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ATP5PO, ATP synthase peripheral stalk subunit OSCP
  • Synonyms
    ATP5O, ATPO, HMC08D05, MC5DN7, OSCP
  • Links
    NCBI Gene ID: 539
    UniProt: P48047

  • Chr Location
    21q22.11; chr21:33901028-33915853 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human ATP5PO associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    4 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    81 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    34
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    217
  • Tissues
    170
  • cDNA Data
    326
  • Literature Summary
    7
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 28080 NCBI Gene Model | MGI Sequence Detail 6408 C57BL/6J ±  kb
transcript NM_138597 RefSeq | MGI Sequence Detail 772 C57BL/6  
polypeptide Q9DB20 UniProt | EBI | MGI Sequence Detail 213 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    7 Sequences
  • Protein Ontology
    PR:000004465 ATP synthase peripheral stalk subunit OSCP, mitochondrial
    (term hierarchy)
  • InterPro Domains
    IPR000711 ATPase, OSCP/delta subunit
    IPR020781 ATPase, OSCP/delta subunit, conserved site
    IPR024861 Donson
    IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily
    IPR060529 Protein downstream neighbor of Son domain
  • GlyGen
    Q9DB20 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 329
    cDNA 326
    Primer pair 2
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-34033, MGI:7469653
References
more
  • Summaries
    All 130
    Developmental Gene Expression 7
    Diseases 4
    Gene Ontology 11
    Phenotypes 81
  • Earliest
    J:42265 Huang TT, et al., Superoxide-mediated cytotoxicity in superoxide dismutase-deficient fetal fibroblasts. Arch Biochem Biophys. 1997 Aug 15;344(2):424-32
  • Latest
    J:385727 Harada K, et al., Preventing Differentiation Towards Primitive Macrophages in Stem Cells With Down Syndrome. Immunology. 2026 Mar;177(3):596-612
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory