Sequence Detail

ID/Version

Q9WVI9 Q9R1H9 Q925J8 Q9WVI8 O35145 Q9R1Z1 Q9WVI7 (UniProt | EBI)

Last sequence update: 2001-12-05
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=C-Jun-amino-terminal kinase-interacting protein 1; Short=JIP-1; Short=JNK-interacting protein 1;AltName: Full=Islet-brain-1; Short=IB-1;AltName: Full=JNK MAP kinase scaffold protein 1;AltName: Full=Mitogen-activated p

Provider

SWISS-PROT

Sequence

Polypeptide 707 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1	54	109	4	17

Sequence references in MGI

J:50502 Dickens M, et al., A cytoplasmic inhibitor of the JNK signal transduction pathway. Science. 1997 Aug 1;277(5326):693-6
J:53500 Kim IJ, et al., Molecular cloning of multiple splicing variants of JIP-1 preferentially expressed in brain. J Neurochem. 1999 Apr;72(4):1335-43
J:58705 Meyer D, et al., Interaction of c-Jun amino-terminal kinase interacting protein-1 with p190 rhoGEF and its localization in differentiated neurons. J Biol Chem. 1999 Dec 3;274(49):35113-8
J:70827 Ehringer MA, et al., High-throughput sequence identification of gene coding variants within alcohol-related QTLs. Mamm Genome. 2001 Aug;12(8):657-63
J:77616 Whitmarsh AJ, et al., Requirement of the JIP1 scaffold protein for stress-induced JNK activation. Genes Dev. 2001 Sep 15;15(18):2421-32
J:109088 Coquelle FM, et al., Common and divergent roles for members of the mouse DCX superfamily. Cell Cycle. 2006 May;5(9):976-83
J:113792 Yasuda J, et al., The JIP group of mitogen-activated protein kinase scaffold proteins. Mol Cell Biol. 1999 Oct;19(10):7245-54
J:113901 Gotthardt M, et al., Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction. J Biol Chem. 2000 Aug 18;275(33):25616-24
J:113982 Taru H, et al., Interaction of Alzheimer's beta -amyloid precursor family proteins with scaffold proteins of the JNK signaling cascade. J Biol Chem. 2002 May 31;277(22):20070-8
J:114032 Verhey KJ, et al., Cargo of kinesin identified as JIP scaffolding proteins and associated signaling molecules. J Cell Biol. 2001 Mar 5;152(5):959-70
J:114833 Pellet JB, et al., Spatial, temporal and subcellular localization of islet-brain 1 (IB1), a homologue of JIP-1, in mouse brain. Eur J Neurosci. 2000 Feb;12(2):621-32
J:205863 Cunningham CA, et al., The POSH/JIP-1 scaffold network regulates TCR-mediated JNK1 signals and effector function in CD8(+) T cells. Eur J Immunol. 2013 Dec;43(12):3361-71
J:261832 Cunningham CA, et al., POSH Regulates CD4+ T Cell Differentiation and Survival. J Immunol. 2016 May 15;196(10):4003-13
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89