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Sequence Detail
ID/Version
Q8BTY2 Q3U5H7 (UniProt | EBI) Last sequence update: 2006-02-07
Last annotation update: 2023-11-08
Sequence
description
from provider
RecName: Full=Sodium bicarbonate cotransporter 3;AltName: Full=Solute carrier family 4 member 7;
Provider SWISS-PROT
Sequence
Polypeptide 1034 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Slc4a7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 42 99 3 19
Sequence references in MGI J:86635 Bok D, et al., Blindness and auditory impairment caused by loss of the sodium bicarbonate cotransporter NBC3. Nat Genet. 2003 Jul;34(3):313-9
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:106804 Reiners J, et al., Scaffold protein harmonin (USH1C) provides molecular links between Usher syndrome type 1 and type 2. Hum Mol Genet. 2005 Dec 15;14(24):3933-43
J:118990 Boedtkjer E, et al., NBCn1 (slc4a7) mediates the Na+-dependent bicarbonate transport important for regulation of intracellular pH in mouse vascular smooth muscle cells. Circ Res. 2006 Mar 3;98(4):515-23
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:200059 Chen M, et al., The electroneutral Na(+):HCO(3)(-) cotransporter NBCn1 is a major pHi regulator in murine duodenum. J Physiol. 2012 Jul 15;590(Pt 14):3317-33
J:208247 Singh AK, et al., Essential role of the electroneutral Na+-HCO3- cotransporter NBCn1 in murine duodenal acid-base balance and colonic mucus layer build-up in vivo. J Physiol. 2013 Apr 15;591(Pt 8):2189-204
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:307106 Choi I, et al., Sodium bicarbonate cotransporter NBCn1/Slc4a7 affects locomotor activity and hearing in mice. Behav Brain Res. 2021 Mar 5;401:113065

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory