Sequence Detail

ID/Version

Q61088 (UniProt | EBI)

Last sequence update: 1996-11-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Frizzled-4; Short=Fz-4; Short=mFz4;AltName: CD_antigen=CD344;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 537 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fzd4	frizzled class receptor 4	95	125	3	15

Sequence references in MGI

J:37068 Wang Y, et al., A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled. J Biol Chem. 1996 Feb 23;271(8):4468-76
J:107732 Xu Q, et al., Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair. Cell. 2004 Mar 19;116(6):883-95
J:154863 Junge HJ, et al., TSPAN12 regulates retinal vascular development by promoting Norrin- but not Wnt-induced FZD4/beta-catenin signaling. Cell. 2009 Oct 16;139(2):299-311
J:163736 Yao R, et al., MAGI-3 is involved in the regulation of the JNK signaling pathway as a scaffold protein for frizzled and Ltap. Oncogene. 2004 Aug 12;23(36):6023-30
J:175224 Ohta K, et al., Tsukushi functions as a Wnt signaling inhibitor by competing with Wnt2b for binding to transmembrane protein Frizzled4. Proc Natl Acad Sci U S A. 2011 Sep 6;108(36):14962-7