Sequence Detail

ID/Version

P56542 O55053 (UniProt | EBI)

Last sequence update: 1998-07-15
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Deoxyribonuclease-2-alpha; EC=3.1.22.1;AltName: Full=Acid DNase;AltName: Full=Deoxyribonuclease II alpha; Short=DNase II alpha;AltName: Full=Lysosomal DNase II;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 353 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Dnase2a	deoxyribonuclease II alpha	8	98	3	11

Sequence references in MGI

J:49551 Baker KP, et al., Molecular cloning and characterization of human and murine DNase II. Gene. 1998 Jul 30;215(2):281-9
J:63631 Krieser RJ, et al., Deoxyribonuclease II: structure and chromosomal localization of the murine gene, and comparison with the genomic structure of the human and three C. elegans homologs. Gene. 2000 Jul 11;252(1-2):155-62
J:69831 Kawane K, et al., Requirement of DNase II for definitive erythropoiesis in the mouse fetal liver. Science. 2001 May 25;292(5521):1546-9
J:89469 Krieser RJ, et al., Deoxyribonuclease IIalpha is required during the phagocytic phase of apoptosis and its loss causes perinatal lethality. Cell Death Differ. 2002 Sep;9(9):956-62
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89