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Tg(ITGAM-cre/ERT2)F9Jckr - Head
Recombinase Activity Detail
Allele Information
Allele:
Tg(ITGAM-cre/ERT2)F9Jckr
transgene insertion, Mathias Jucker 		Driver: ITGAM
Type: Transgenic (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: CD11b-CreERT2
Molecular description: The transgene consists of the 1,723-bp human CD11b (ITGAM) promoter, a 2,578-bp fragment encoding a rabbit -globin intron and the CreERT2 sequence, a 603-bp transcript-stabilizing WPRE sequence and a 170-bp spanning SV-40 poly(A) sequence. Three founder lines were generated. information and line numbers were not available. The founder line with the most robust and microglia-specific recombination was chosen for further breeding (F9 line).
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(ITGAM-cre/ERT2)F9Jckr activity also observed in:
nervous system
Tissue Information
Head Other recombinase alleles with activity in Head tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory