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MTY811C Probe Detail
Nucleotide
Probe/Clone
  • Name
    MTY811C
  • Sequence Type
    cDNA
  • ID
    MGI:15274
  • Region Covered
    most of coding region and 3' flank sequence
  • Vector Type
    Phage
  • Insert Site
    EcoRI/HindIII
  • Insert Size
    1.4 kb
  • Synonyms
    MTY811
Source
  • Species
    mouse, laboratory
  • Tissue
    melanocyte
  • Cell Line
    melanoma cell line Cloudman S91
Genes
Tyr tyrosinase
Polymorphisms
J:9824 Kwon BS, et al., Biochem Biophys Res Commun. 1989 May 30;161(1):252-60
Notes: The himilayan, c, mutation originated in >a< DBA/2J X AKR/J cross and therefore the RFLV detected may reflect the DBA/2J origin rather that the c mutation.
Endonuclease Gene Allele Fragments Strains
EcoRI Tyr b 12.0,8.0,4.5,0.6kb AKR/J, B10.D2-H2d, BALB/c, C57BL/6J
c 17.0,8.0,4.5,0.6kb C57BL/6J, CBA/J, DBA/2J, STOCK Tyrc-h
J:10342 Saunders AM, et al., Genomics. 1990 Feb;6(2):324-32
Endonuclease Gene Allele Fragments Strains
TaqI Tyr c absent C3H/HeJ
s 8.0kb M. spretus
J:11428 Pritchard MA, et al., Genomics. 1991 Jul;10(3):801-6
Endonuclease Gene Allele Fragments Strains
TaqI Tyr b 10.6,8.2,3.7,2.7,1.5,1.4,0.5kb C57BL/6J
s 12.5,8.3,4.4,1.4,0.5kb M. spretus
References
J:9242 Kwon BS, et al., Sequence analysis of mouse tyrosinase cDNA and the effect of melanotropin on its gene expression. Biochem Biophys Res Commun. 1988 Jun 30;153(3):1301-9
J:9824 Kwon BS, et al., Molecular basis of mouse Himalayan mutation. Biochem Biophys Res Commun. 1989 May 30;161(1):252-60
J:10342 Saunders AM, et al., The syntenic relationship of proximal mouse chromosome 7 and the myotonic dystrophy gene region on human chromosome 19q. Genomics. 1990 Feb;6(2):324-32
J:10993 Saunders AM, et al., A molecular genetic linkage map of mouse chromosome 7. Genomics. 1990 Nov;8(3):525-35
J:11428 Pritchard MA, et al., The interleukin-4 receptor gene (IL4R) maps to 16p11.2-16p12.1 in human and to the distal region of mouse chromosome 7. Genomics. 1991 Jul;10(3):801-6
J:4272 Rinchik EM, et al., Molecular analysis of viable spontaneous and radiation-induced albino (c)-locus mutations in the mouse. Mutat Res. 1993 Apr;286(2):199-207
J:15677 Rinchik EM, et al., Molecular analysis of radiation-induced albino (c)-locus mutations that cause death at preimplantation stages of development. Genetics. 1993 Dec;135(4):1107-16
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/03/2024
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