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MGF-4 Probe Detail
Nucleotide
Probe/Clone
  • Name
    MGF-4
  • Sequence Type
    cDNA
  • ID
    MGI:14934
  • Region Covered
    full length cDNA (NTds 40-993, amino acids 1-41)
  • Vector Type
    Phage
  • Insert Size
    1.0kb
  • Note
    Mgf is near or equivalent to the Sl locus.
  • Synonyms
    pMGF-4
Source
  • Species
    mouse, laboratory
  • Tissue
    stromal cells
  • Tissue Description
    bone marrow derived stromal cells
Genes
Kitl kit ligand
Sequences
M38436 (GenBank | EMBL | ENA | DDBJ | MGI Sequence Detail)
Polymorphisms
J:3252 King TR, et al., Genomics. 1991 Oct;11(2):273-83
Endonuclease Gene Allele Fragments Strains
MspI Kitl a 9.0kb BALB/cJ
c 10.5kb CAST/EiJ
J:20286 Brannan CI, et al., Proc Natl Acad Sci U S A. 1991 Jun 1;88(11):4671-4
Notes: A 1 kb SalI fragment was isolated from MGF.4 and used in Southern analysis. Several other subfragments of MGF.4 are shown to be useful in demonstrating these EcoRI and HindIII RFLVs.
Endonuclease Gene Allele Fragments Strains
EcoRI Kitl + 12.0,11.0,8.5,6.4,3.9kb C57BL/6J
Sl/+ 11.0,8.5,8.0,6.4,3.9kb B6.D2-KitlSl-d/J
HindIII Kitl + 3.5kb C57BL/6J
Sl absent B6.D2-KitlSl-d/J
J:21383 Scholzen T, et al., J Biol Chem. 1994 Nov 11;269(45):28270-81
Endonuclease Gene Allele Fragments Strains
Not Specified Kitl a not given AEJ/Gn
s not given M. spretus
References
J:10748 Copeland NG, et al., Mast cell growth factor maps near the steel locus on mouse chromosome 10 and is deleted in a number of steel alleles. Cell. 1990 Oct 5;63(1):175-83
J:10752 Anderson DM, et al., Molecular cloning of mast cell growth factor, a hematopoietin that is active in both membrane bound and soluble forms [published erratum appears in Cell 1990 Nov 30;63(5):following 1112]. Cell. 1990 Oct 5;63(1):235-43
J:3252 King TR, et al., Mapping anti-mullerian hormone (Amh) and related sequences in the mouse: identification of a new region of homology between MMU10 and HSA19p. Genomics. 1991 Oct;11(2):273-83
J:20286 Brannan CI, et al., Steel-Dickie mutation encodes a c-kit ligand lacking transmembrane and cytoplasmic domains. Proc Natl Acad Sci U S A. 1991 Jun 1;88(11):4671-4
J:21383 Scholzen T, et al., The murine decorin. Complete cDNA cloning, genomic organization, chromosomal assignment, and expression during organogenesis and tissue differentiation. J Biol Chem. 1994 Nov 11;269(45):28270-81
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory