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VGAM3-2 Probe Detail
Nucleotide
Probe/Clone
  • Name
    VGAM3-2
  • Sequence Type
    genomic
  • ID
    MGI:13602
  • Region Covered
    encodes Igh-V3660 gene segment VGAM3-2, an Igh-D gene segment (DSP2.2), two Igh-J gene segments (J3-4), and the Igh-8 gene segments
  • Vector Type
    Phage
Source
  • Species
    mouse, laboratory
  • Strain
    (C57BL/6 x BALB/c)F1
  • Tissue
    lymphocyte
  • Tissue Description
    spleen derived lymphocyte
Genes
Igh-8 immunoglobulin heavy chain 8 (heavy chain of IgG3)
Igh-D immunoglobulin heavy chain diversity region
Igh-J immunoglobulin heavy chain, joining region
Igh-V3660 immunoglobulin heavy chain (V3660 family)
Polymorphisms
J:8840 Blankenstein T, et al., Eur J Immunol. 1987 Sep;17(9):1351-7
Endonuclease Gene Allele Fragments Strains
EcoRI Igh-V3660 a multiple BALB/c
b multiple C57BL/6
c multiple CAST/EiJ
d multiple MOLF/EiJ
e multiple M. m. musculus
f multiple CB20
HindIII Igh-V3660 a multiple BALB/c
b multiple C57BL/6
c multiple CAST/EiJ
d multiple MOLF/EiJ
e multiple M. m. musculus
f multiple CB20
References
J:8090 Winter E, et al., Members of novel VH gene families are found in VDJ regions of polyclonally activated B-lymphocytes. EMBO J. 1985 Nov;4(11):2861-7
J:8840 Blankenstein T, et al., Immunoglobulin VH region genes of the mouse are organized in overlapping clusters [published erratum appears in Eur J Immunol 1987 Nov;17(11):1680]. Eur J Immunol. 1987 Sep;17(9):1351-7
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory