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Tu66 Probe Detail
Nucleotide
Probe/Clone
  • Name
    Tu66
  • Sequence Type
    genomic
  • ID
    MGI:13402
  • Vector Type
    Plasmid
  • Insert Site
    EcoRI
  • Insert Size
    0.5kb
Source
  • Species
    mouse, laboratory
  • Age
    embryonic
  • Tissue
    fibroblast
Genes
D17Leh66 DNA segment, Chr 17, Lehrach 66
D17Leh66EI DNA segment, Chr 17, Lehrach 66EI
D17Leh66EII DNA segment, Chr 17, Lehrach 66EII
Tcp10a t-complex protein 10a
Tcp10b t-complex protein 10b
Tcp10c t-complex protein 10c
Polymorphisms
J:7707 Fox HS, et al., Cell. 1985 Jan;40(1):63-9
Notes: Strain and/or t haplotype designations appear in allele groupings.
Endonuclease Gene Allele Fragments Strains
BamHI Tcp10b a 17.5kb C3.t0, C3.t6, C3.tw5, C3.tw12, C3.tw18, C3H-tw2, STOCK t3, STOCK t4, STOCK th2, STOCK th17, STOCK th20, STOCK th49, STOCK tLmb, STOCK tlow3H, STOCK tlowH, STOCK ts6, STOCK tw32, STOCK twLub1, STOCK twLub2, STOCK twLub7
b absent 129X1/SvJ, (129 x tAE5)F1, A/J, AKR/J, BALB/cJ, C3H/HeJ, C57BL/6J, C57BL/10J, C58/J, CBA/CaJ, DBA/1J, DBA/2J, LG/J, LT/ChReJ, NZB/BlNJ, RF/J, SM/J, STOCK Del(17)TOrl, STOCK th18, STOCK th44, STOCK th45, STOCK th51, STOCK th53, STOCK tTu2, SWR/J, WLA76
TaqI Tcp10a a 6.2kb C3.t0, C3.t6, C3.tw5, C3.tw12, C3.tw18, C3H-tw2, STOCK t3, STOCK t4, STOCK th2, STOCK th20, STOCK th44, STOCK th49, STOCK th51, STOCK th53, STOCK tLmb, STOCK tLub2, STOCK tw32, STOCK twLub1, STOCK twLub7
b absent 129X1/SvJ, (129 x tAE5)F1, A/J, AKR/J, BALB/cJ, C3H/HeJ, C57BL/6J, C57BL/10J, C58/J, CBA/CaJ, DBA/1J, DBA/2J, LG/J, LT/ChReJ, NZB/BlNJ, RF/J, SM/J, STOCK Del(17)TOrl, STOCK th17, STOCK th18, STOCK th45, STOCK tlow3H, STOCK tlowH, STOCK ts6, STOCK tTu2, SWR/J, WLA76
TaqI Tcp10c a .8kb C3.t0, C3.t6, C3.tw5, C3.tw12, C3.tw18, C3H-tw2, STOCK t3, STOCK t4, STOCK th17, STOCK th20, STOCK tLmb, STOCK ts6, STOCK tw32, STOCK twLub1, STOCK twLub2, STOCK twLub7
b absent 129X1/SvJ, (129 x tAE5)F1, A/J, AKR/J, BALB/cJ, C3H/HeJ, C57BL/6J, C57BL/10J, C58/J, CBA/CaJ, DBA/1J, DBA/2J, LG/J, LT/ChReJ, NZB/BlNJ, RF/J, SM/J, STOCK Del(17)TOrl, STOCK th2, STOCK th18, STOCK th44, STOCK th45, STOCK th49, STOCK th51, STOCK th53, STOCK tlow3H, STOCK tlowH, STOCK tTu2, SWR/J, WLA76
J:8163 Herrmann B, et al., Cell. 1986 Feb 14;44(3):469-76
Notes: Strain and t haplotype designations appear in the allele groupings. The locus D17Leh66E has been split into D17Leh66EI and D17Leh66EII. The probe Tu66 has been shown to hybridize to both D17Leh66EI and D17Leh66EII, but it is not clear which of the fragments reported in the RFLP data shown here represent D17Leh66EI and which represent D17Leh66EII. For this reason the RFLP data will be associated with the original parent locus, D17Leh66E.
Endonuclease Gene Allele Fragments Strains
Tcp10c a ~1kb C3.tw5
b absent 129/Sv, STOCK Del(17)TOrl, STOCK t3, STOCK twLub2
Not Specified D17Leh66EI a not given DBA/2J
b not given C57BL/6J
TaqI D17Leh66EI a 9.5kb 129/Sv, STOCK th17
c 9.5,4.5kb C3.tw5, STOCK twLub2
d absent STOCK Del(17)TOrl
TaqI Tcp10a a ~6.2kb C3.tw5, C3.tw18, STOCK t3, STOCK th2, STOCK th44, STOCK th49, STOCK th51, STOCK th53, STOCK twLub2
b absent 129/Sv, (129 x tAE5)F1, STOCK Del(17)TOrl, STOCK th17, STOCK th18, STOCK th45, STOCK tTu2
J:8496 Gallahan D, et al., J Virol. 1987 Jan;61(1):218-20
Endonuclease Gene Allele Fragments Strains
TaqI D17Leh66 a 1.8,1.5kb C3H/HeOuJ
c absent CZECHII
J:26135 Shustrova IV, et al., Genetika. 1995 May;31(5):622-31
Notes: Tu66 has been reported to hybridize with several loci in the region of D17Leh66. The authors do not indicate which loci these RFLP bands are derived from. Strain and t haplotype designations appear in allele groupings.
Endonuclease Gene Allele Fragments Strains
BamHI D17Leh66 d 20.1,6.2,5.8,3.8kb M. m. domesticus
e 20.1,5.8,3.8kb M. m. domesticus
f 23.0,20.1,15.2kb STOCK T
t 23.0,17.5,15.2,6.2,5.8kb C3.t12, C3.tw5, C3.tw12, C3.tw18, C3.tw73, STOCK tM8, STOCK tM9, STOCK tMC1, STOCK twMp1, STOCK twPas1
TaqI D17Leh66 b 9.4,4.5,2.5,1.5kb C57BL/6, CBA/CaLac
c 4.5,2.5,1.7,1.5kb BALB/cJ
d 9.4,4.7,4.5,2.5,1.7,1.5kb M. m. domesticus
e 9.4,4.7,4.5,2.5,1.5kb M. m. domesticus, STOCK T
f 4.5,2.5,1.5kb M. abbotti, M. hortulanus, M. m. musculus
t 6.5,4.5,2.5,1.5,0.8kb C3.t12, C3.tw5, C3.tw12, C3.tw18, C3.tw73, STOCK tM8, STOCK tM9, STOCK tMC1, STOCK twMp1, STOCK twPas1
References
J:7328 Rohme D, et al., Molecular clones of the mouse t complex derived from microdissected metaphase chromosomes. Cell. 1984 Mar;36(3):783-8
J:7707 Fox HS, et al., Molecular probes define different regions of the mouse t complex. Cell. 1985 Jan;40(1):63-9
J:8163 Herrmann B, et al., Genetic analysis of the proximal portion of the mouse t complex: evidence for a second inversion within t haplotypes. Cell. 1986 Feb 14;44(3):469-76
J:8496 Gallahan D, et al., A new common integration region (int-3) for mouse mammary tumor virus on mouse chromosome 17. J Virol. 1987 Jan;61(1):218-20
J:15367 Schimenti J, et al., An unstable family of large DNA elements in the center of the mouse t complex. J Mol Biol. 1987 Apr 20;194(4):583-94
J:1694 Hanley-Hyde J, et al., Expression of murine cyclin B1 mRNAs and genetic mapping of related genomic sequences. Genomics. 1992 Aug;13(4):1018-30
J:26135 Shustrova IV, et al., [Polymorphism of t-specific DNA elements of the proximal part of chromosome 17 in mice of Mus genus]. Genetika. 1995 May;31(5):622-31

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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory