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p922 Probe Detail
Nucleotide
Probe/Clone
  • Name
    p922
  • Sequence Type
    cDNA
  • ID
    MGI:12716
  • Region Covered
    contains regions of exons 1 and 2 of Ifi202
  • Child Clone
    202 cDNA
  • Vector Type
    Plasmid
  • Note
    Tumor cells were treated with interferon.
Source
  • Species
    mouse, laboratory
  • Cell Line
    Ehrlich ascites tumor cell line
Genes
Ifi204 interferon activated gene 204
Ifi202a interferon activated gene 202A
Polymorphisms
J:9942 Opdenakker G, et al., Virology. 1989 Aug;171(2):568-78
Notes: Sizes listed for RFLV bands were estimated from gel photographs. A .17 kb Pst1/EcoRI fragment subcloned into pUC19 was used in Southern analysis. This probe cross hybridizes with Ifi204 and Ifi201.
Endonuclease Gene Allele Fragments Strains
EcoRI Ifi202a c ~15,6.7kb C3H/HeJ-Faslgld/J
s ~9.4,8kb M. spretus
TaqI Ifi202a c ~9,8,2.5kb C3H/HeJ-Faslgld/J
s ~4.2,3.8,2.3,1.0kb M. spretus
J:10003 Kingsmore SF, et al., Immunogenetics. 1989;30(3):169-74
Notes: A 170 bp PstI/EcoRI fragment was isolated from p922 and used in Southern analysis. Ifi202 and Ifi204 are both recognized by this fragment.
Endonuclease Gene Allele Fragments Strains
EcoRI Ifi202a c 6.7kb C3H/HeJ-Faslgld/J
s 7.2kb M. spretus
EcoRI Ifi204 c 12.0kb C3H/HeJ-Faslgld/J
s 8.0kb M. spretus
References
J:8394 Samanta H, et al., Interferons as gene activators. Cloning of the 5' terminus and the control segment of an interferon activated gene. J Biol Chem. 1986 Sep 5;261(25):11849-58
J:9942 Opdenakker G, et al., Interferons as gene activators: a cluster of six interferon-activatable genes is linked to the erythroid alpha-spectrin locus on murine chromosome 1. Virology. 1989 Aug;171(2):568-78
J:10003 Kingsmore SF, et al., Physical mapping of a family of interferon-activated genes, serum amyloid P-component, and alpha-spectrin on mouse chromosome 1. Immunogenetics. 1989;30(3):169-74
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory