About   Help   FAQ
pRS48 Probe Detail
Nucleotide
Probe/Clone
  • Name
    pRS48
  • Sequence Type
    cDNA
  • ID
    MGI:11892
  • Region Covered
    most of the coding region, 0.13kb 3' untranslated, poly A tail
  • Vector Type
    Plasmid
  • Insert Site
    PstI
  • Insert Size
    0.43kb
Source
  • Species
    mouse, laboratory
  • Strain
    Swiss
  • Sex
    Male
  • Tissue
    liver
  • Tissue Description
    endotoxin-induced liver
Genes
Saa serum amyloid A cluster
Saa1 serum amyloid A 1
Saa2 serum amyloid A 2
Saa3 serum amyloid A 3
Sequences
M25467 (GenBank | EMBL | ENA | DDBJ | MGI Sequence Detail)
X03479 (GenBank | EMBL | ENA | DDBJ | MGI Sequence Detail)
Polymorphisms
J:7560 Taylor BA, et al., Mol Gen Genet. 1984;195(3):491-9
Endonuclease Gene Allele Fragments Strains
BamHI Saa1 a 10.5,7.2,5.9,2.8,1.3kb A/HeJ, A/J, AKR/J, BALB/cByJ, BALB/cJ, BUB/BnJ, C3H/HeJ, C3HeB/FeJ, C57BL/6J, C57BL/10J, C57BL/10Sn, C57BLKS/J, C57BR/cdJ, C57L/J, C58/J, CBA/CaJ, CBA/J, DBA/1J, DBA/2J, FS/EiJ, HRS/J, LG/J, LP/J, MA/MyJ, NZB/BlNJ, PL/J, RF/J, RIIIS/J, SEC/1ReJ, SF/CamEiJ, SM/J, ST/bJ, SWR/J, YBR/EiJ
b 9.4,7.2,5.9,2.8,1.4kb 129/Sv, 129P3/J, ABP/LeJ, BDP/J, I/LnJ, P/J, PRO/1ReJ, SJL/J
c 10.5,7.2,5.9,2.8,1.4kb IS/Cam, PERA
d 10.5,7.2,6.2,2.8,1.4kb SK/Cam
e 10.5,7.2,5.9,2.9,1.4kb CE/J
f 12.0,7.2,6.8,5.9,2.8,1.4 kb CAST/EiJ
g 10.5,7.2,6.8,5.9,2.8,1.4 kb MOLF/EiJ
BclI Saa1 a 20,8.0,0.7kb C57BL/10Sn
b 8.0,6.0,4.4,0.7kb B10.129-SelenosH47-b/(21M)Sn
c 8.0,3.8,2.3,0.7kb IS/Cam
BglII Saa1 a,c 15.0,4.7,4.0kb C57BL/10Sn, IS/Cam
b 9.4,4.7,4.0kb B10.129-SelenosH47-b/(21M)Sn
EcoRI Saa1 a 7.0,6.0,4.4,2.9kb A/HeJ, A/J, AKR/J, BALB/cByJ, BALB/cJ, BUB/BnJ, C3H/HeJ, C3HeB/FeJ, C57BL/6J, C57BL/10J, C57BL/10Sn, C57BLKS/J, C57BR/cdJ, C57L/J, C58/J, CBA/CaJ, CBA/J, DBA/1J, DBA/2J, FS/EiJ, HRS/J, LG/J, LP/J, MA/MyJ, NZB/BlNJ, PL/J, RF/J, SEC/1ReJ, SF/CamEiJ, SM/J, ST/bJ, SWR/J, YBR/EiJ
b 7.0,4.4,2.9kb 129/Sv, 129P3/J, ABP/LeJ, BDP/J, CAST/EiJ, CE/J, I/LnJ, IS/Cam, MOLF/EiJ, P/J, PERA, PRO/1ReJ, RIIIS/J, SJL/J, SK/Cam
HindIII Saa1 a 10.0,8.0,kb A/HeJ, A/J, AKR/J, BALB/cByJ, BALB/cJ, BUB/BnJ, C3H/HeJ, C3HeB/FeJ, C57BL/6J, C57BL/10J, C57BL/10Sn, C57BLKS/J, C57BR/cdJ, C57L/J, C58/J, CAST/EiJ, CBA/CaJ, CBA/J, DBA/1J, DBA/2J, FS/EiJ, HRS/J, LG/J, LP/J, MA/MyJ, MOL/Ei, NZB/BlNJ, PL/J, RF/J, SEC/1ReJ, SF/CamEiJ, SM/J, ST/bJ, SWR/J, YBR/EiJ
b 10.0,8.0kb 129/Sv, 129P3/J, ABP/LeJ, BDP/J, I/LnJ, P/J, PRO/1ReJ, SJL/J
c 12.7,9.0,6.4kb CE/J, IS/Cam
d 10.0,9.0,3.6,2.1kb RIIIS/J
e 12.7,9.0,3.6kb SK/Cam
f 12.7,9.0,6.4,2.1kb PERA
MspI Saa1 a 2.3,1.9,0.5kb C57BL/10Sn
b 1.8,0.9,0.5kb B10.129-SelenosH47-b/(21M)Sn
c 0.5kb IS/Cam
PvuII Saa1 a 6.4,1.5,1.3kb A/HeJ, A/J, AKR/J, BALB/cByJ, BALB/cJ, BUB/BnJ, C3H/HeJ, C3HeB/FeJ, C57BL/6J, C57BL/10J, C57BL/10Sn, C57BLKS/J, C57BR/cdJ, C57L/J, C58/J, CAST/EiJ, CBA/CaJ, CBA/J, CE/J, DBA/1J, DBA/2J, FS/EiJ, HRS/J, IS/Cam, LG/J, LP/J, MA/MyJ, NZB/BlNJ, PERA, PL/J, RF/J, RIIIS/J, SEC/1ReJ, SF/CamEiJ, SK/Cam, SM/J, ST/bJ, SWR/J, YBR/EiJ
b 7.2,1.8,1.5kb 129/Sv, 129P3/J, ABP/LeJ, BDP/J, I/LnJ, MOLF/EiJ, P/J, PRO/1ReJ, SJL/J
SstI Saa1 a 8.0,4.7kb C57BL/10Sn
b,c 9.2,8.0,5.0kb B10.129-SelenosH47-b/(21M)Sn, IS/Cam
References
J:6644 Morrow JF, et al., Induction of hepatic synthesis of serum amyloid A protein and actin. Proc Natl Acad Sci U S A. 1981 Aug;78(8):4718-22
J:17551 Stearman RS, et al., Regulation of synthesis of amyloid A-related protein. Ann N Y Acad Sci. 1982;389:106-15
J:7560 Taylor BA, et al., Genes for serum amyloid A proteins map to Chromosome 7 in the mouse. Mol Gen Genet. 1984;195(3):491-9
J:8180 Stearman RS, et al., The sequence and structure of a new serum amyloid A gene. Nucleic Acids Res. 1986 Jan 24;14(2):797-809
J:9600 Rienhoff HY Jr, et al., Regulation of amyloid A gene expression in cultured cells. Mol Cell Biol. 1988 Sep;8(9):3710-6
J:10993 Saunders AM, et al., A molecular genetic linkage map of mouse chromosome 7. Genomics. 1990 Nov;8(3):525-35
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory