c50.2.1 Probe Detail MGI Mouse MGI:11536

c50.2.1 Probe Detail

Name

c50.2.1
Sequence Type

genomic
ID

MGI:11536
Parent Clone

cosmid 50.2
Vector Type

Phage
Insert Site

HincII
Insert Size

2.0kb
Note

Insert also exits in pUC18.

Species

mouse, laboratory
Strain

BALB/c
Tissue

sperm

H2-D1	histocompatibility 2, D region locus 1
H2-D3	histocompatibility 2, D region locus 3
H2-Q	histocompatibility 2, Q region
H2-Q1	histocompatibility 2, Q region locus 1
H2-Q2	histocompatibility 2, Q region locus 2
H2-Q3	histocompatibility 2, Q region locus 3
H2-T	histocompatibility 2, T region

J:7080 Winoto A, et al., Proc Natl Acad Sci U S A. 1983 Jun;80(11):3425-9

Endonuclease	Gene	Allele	Fragments	Strains
KpnI	H2-D3	a	10.5kb	BALB/c
		b	16kb	C3H, C57BL/6-H2^k
		c	13kb	B6.K2, B10.A-H2^h1/(1R), C57BL/6, C57BL/6-H2-T18^a
		d	absent	A.AL-H2^a1, A.BY-H2^bc H2-T18^f/SnJ, A.TL-H2^t1, A/WySnJ, AKR, AQR, B10.A-H2^a, B10.A-H2ⁱ³/(3R), B10.AKM-H2^m/SnJ, B10.BDR1-H2^g4, B10.D2-H2^d, B10.Q-H2^q/SgJ, C57BL/10

J:8531 O'Neill AE, et al., Immunogenetics. 1986;24(6):368-73

Endonuclease	Gene	Allele	Fragments	Strains
PstI	H2-D1	a	3.6kb	B6.K1
PstI	H2-D1	b	absent	B6.AK1
PstI	H2-Q	a	7.1,6.5,6.0,5.9kb	B6.AC2, B6.AC3, C57BL/6
		b	14kb	B6.K1
		c	absent	A.CA-H2^f/Sn, B6.K2, B10.M-H2^f/Sn
PstI	H2-T	a	20,4.4kb	A.CA-H2^f/Sn, B6.AC2, B6.AC3, C57BL/6-H2^k
PstI	H2-T	b	absent	B6.AC1, B6.K4

J:557 Uehara H, et al., Mamm Genome. 1991;1(2):92-9

Notes: t haplotype designations appear in the allele groupings.

Endonuclease	Gene	Allele	Fragments	Strains
BamHI	H2-Q	a	multiple	A/J, C3.t¹², STOCK t^w32
		b	multiple	C3.t⁰, C3.t^w8, C57BL/10
		c	multiple	C3H-t^w2, DBA/2, STOCK t^wPas1
		d	multiple	C3.t^Lub1, P/J
		e	multiple	C3.t⁶, C3.t^w1, C3.t^w12, RIIIS/J
		f	multiple	A.SW-H2^s H2-T18^b/SnJ, C3.t^w130, C3H-t^w71
		g	multiple	BALB/c, C3.t^w73, PL/J
		h	multiple	C3.t^w121, SM/J
		i	multiple	C3.t^w5, C3.t^w120, NZB
		j	multiple	C3.t^w75, C57BL/6

J:7080 Winoto A, et al., Genetic mapping in the major histocompatibility complex by restriction enzyme site polymorphisms: most mouse class I genes map to the Tla complex. Proc Natl Acad Sci U S A. 1983 Jun;80(11):3425-9

J:8531 O'Neill AE, et al., Extensive deletions in the Q region of the mouse major histocompatibility complex. Immunogenetics. 1986;24(6):368-73

J:557 Uehara H, et al., Molecular organization of the D-Qa region of t-haplotypes suggests that recombination is an important mechanism for generating genetic diversity of the major histocompatibility complex. Mamm Genome. 1991;1(2):92-9

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