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Cyp21 genomic1 Probe Detail
Nucleotide
Probe/Clone
  • Name
    Cyp21 genomic1
  • Sequence Type
    genomic
  • ID
    MGI:11497
  • Region Covered
    encodes Cyp21 exon 2, intron 2 and exon 3
  • Parent Clone
    E-7
  • Vector Type
    Phage
  • Insert Site
    BamHI/EcoRI
  • Insert Size
    821bp
  • Note
    This segment encodes that portion of the gene that has been deleted in pseudogene Cyp21-ps1.
Source
  • Species
    mouse, laboratory
  • Strain
    BALB/c
  • Tissue
    plasma cell
  • Cell Line
    myeloma cell line MOPC 321
Genes
Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1
Cyp21a2-ps cytochrome P450, family 21, subfamily a, polypeptide 2 pseudogene
Sequences
M15009 (GenBank | EMBL | ENA | DDBJ | MGI Sequence Detail)
Polymorphisms
J:8544 Chaplin DD, et al., Proc Natl Acad Sci U S A. 1986 Dec;83(24):9601-5
Notes: The 1.7 and 1.9 kb fragments encode portions of Cyp21-ps1 and Cyp21 (respectively). The gene associated with the 1.8 kb fragment is not indicated.
Endonuclease Gene Allele Fragments Strains
ApaI Cyp21a1 b 1.7,1.9kb BALB/c, C57BL/6, DBA/2J
c 1.8kb C3H/HeJ
References
J:8544 Chaplin DD, et al., Nucleotide sequence analysis of murine 21-hydroxylase genes: mutations affecting gene expression. Proc Natl Acad Sci U S A. 1986 Dec;83(24):9601-5
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory