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NT18 Probe Detail
Nucleotide
Probe/Clone
  • Name
    NT18
  • Sequence Type
    cDNA
  • ID
    MGI:10499
  • Region Covered
    coding sequence and flanks
  • Insert Site
    EcoRI
  • Insert Size
    1.8 kb
  • Synonyms
    pNT18
Source
  • Species
    mouse, laboratory
  • Strain
    C57BL/Ka
  • Tissue
    thymus
Genes
Lck lymphocyte protein tyrosine kinase
Polymorphisms
J:4474 Huppi K, et al., Curr Top Microbiol Immunol. 1988;137:276-88
Endonuclease Gene Allele Fragments Strains
EcoRV Lck a 23kb AKR/N, BALB/cAn, BALB/cByJ, BALB/cHeA, DBA/2N, NZB/BlNJ, SJL/JLwPt, STS/A, SWR/J
b 14kb C57BL/6J, C57BL/10ScSnJ, C57L/J, C58/J
StuI Lck a not given AKR/N, BALB/cAn, BALB/cByJ, BALB/cHeA, DBA/2N, NZB/BlNJ, SJL/JLwPt, STS/A, SWR/J
b not given C57BL/6J, C57BL/10ScSnJ, C57L/J, C58/J
J:10133 Ceci JD, et al., Genomics. 1989 Nov;5(4):699-709
Endonuclease Gene Allele Fragments Strains
PvuII Lck b 4.0,2.4,1.6kb C57BL/6J
s 3.6,2.7,1.8kb M. spretus
J:10819 Bahary N, et al., Proc Natl Acad Sci U S A. 1990 Nov;87(21):8642-6
Notes: M.spretus vs. C57BL/6J-db/db alleles stated as differing also; endonuclease used and fragment sizes not specified. Probe name not given in this reference; inferred from the source and source reference for the probe.
Endonuclease Gene Allele Fragments Strains
BglII Lck b absent C57BL/6J
d 3.5,1.7kb DBA/2J
J:3321 Bahary N, et al., Genomics. 1991 Sep;11(1):33-47
Notes: Three ~10.0kb fragments appear in the b allele grouping.
Endonuclease Gene Allele Fragments Strains
BglII Lck b ~10.0kb C57BL/6J
s ~10.0,6.0,4.8,3.2kb M. spretus
J:11192 Fletcher C, et al., Genomics. 1991 Apr;9(4):647-55
Notes: Only differential fragments listed; additional bands visible on autoradiograms. A 1750 bp fragment of clone pNT18 used for Southern analysis.
Endonuclease Gene Allele Fragments Strains
PvuII Lck b absent BKS.Cg-mea2J Dock7m
c ~5,~2kb M. m. castaneus
J:4958 Taylor BA, et al., Genomics. 1993 May;16(2):380-94
Endonuclease Gene Allele Fragments Strains
PvuII Lck c 4.3,2.6,1.9,1.6kb CAST/EiJ
m 4.0,1.8,1.6kb MEV/Ty
J:13235 Lobach DF, et al., Genomics. 1993 Jul;17(1):194-204
Endonuclease Gene Allele Fragments Strains
TaqI Lck c 3.6,3.0,1.6kb C3H/HeJ-Faslgld/J
s 4.5,3.8,2.7kb M. spretus
References
J:8130 Marth JD, et al., A lymphocyte-specific protein-tyrosine kinase gene is rearranged and overexpressed in the murine T cell lymphoma LSTRA. Cell. 1985 Dec;43(2 Pt 1):393-404
J:4474 Huppi K, et al., Organization of the distal end of mouse chromosome 4. Curr Top Microbiol Immunol. 1988;137:276-88
J:10133 Ceci JD, et al., A molecular genetic linkage map of mouse chromosome 4 including the localization of several proto-oncogenes. Genomics. 1989 Nov;5(4):699-709
J:10819 Bahary N, et al., Molecular mapping of the mouse db mutation. Proc Natl Acad Sci U S A. 1990 Nov;87(21):8642-6
J:3321 Bahary N, et al., Molecular genetic linkage maps of mouse chromosomes 4 and 6. Genomics. 1991 Sep;11(1):33-47
J:11192 Fletcher C, et al., Genetic mapping of meander tail, a mouse mutation affecting cerebellar development. Genomics. 1991 Apr;9(4):647-55
J:4958 Taylor BA, et al., The MEV mouse linkage testing stock: mapping 30 novel proviral insertions and establishment of an improved stock. Genomics. 1993 May;16(2):380-94
J:13235 Lobach DF, et al., Nucleotide sequence, expression, and chromosomal mapping of Mrp and mapping of five related sequences. Genomics. 1993 Jul;17(1):194-204

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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory