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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Gja8
gap junction protein, alpha 8
MGI:99953
23 phenotypes from 11 alleles in 16 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gja8Aey5/Gja8+
C3HeB/FeJ-Gja8Aey5 		abnormal lens fiber morphology J:74555
cataract J:74555
small lens J:74555
Gja8Aey5/Gja8Aey5
C3HeB/FeJ-Gja8Aey5 		abnormal lens fiber morphology J:74555
cataract J:74555
small lens J:74555
Gja8dcm/Gja8dcm
BALB/c-Gja8dcm 		abnormal cornea morphology J:91434
abnormal iris morphology J:91434
abnormal lens fiber morphology J:91434
abnormal optic stalk morphology J:91434
abnormal pupil morphology J:91434
abnormal retina morphology J:91434
cataract J:91434
increased body weight J:91434
microphthalmia J:91434
Gja8L1/Gja8+
involves: C3H/HeJ * C57BL/6J 		abnormal lens fiber morphology J:108522
cataract J:108522
lens vacuoles J:108522
microphthalmia J:108522
ruptured lens capsule J:108522
Gja8L1/Gja8L1
involves: C3H/HeJ * C57BL/6J 		abnormal lens fiber morphology J:108522
cataract J:108522
lens vacuoles J:108522
microphthalmia J:108522
ruptured lens capsule J:108522
Gja8L1/Gja8tm1Scr
involves: 129S1/Sv * 129X1/SvJ * C3H/HeJ * C57BL/6J 		microphthalmia J:108522
total cataract J:108522
normal vision/eye phenotype J:108522
Gja8Lop10/Gja8+
C;AK-Gja8Lop10/J 		nuclear cataract J:4160
Gja8Lop10/Gja8Lop10
C;AK-Gja8Lop10/J 		abnormal lens development J:75387
abnormal lens fiber morphology J:75387
cataract J:4160, J:75387
microphthalmia J:4160
ruptured lens capsule J:75387
Gja8Lop10/Gja8tm1Scr
involves: 129S4/SvJae * AKR/J * BALB/cJ * C57BL/6J 		cataract J:75387
microphthalmia J:75387
Gja8No2/Gja8+
involves: 101 * C3H 		nuclear cataract J:49492
Gja8No2/Gja8No2
involves: 101 * C3H 		nuclear cataract J:49492
Gja8R205G/Gja8+
B6.Cg-Gja8R205G 		nuclear cataract J:195727
small lens J:195727
Gja8R205G/Gja8+
CWXS/Agl-Gja8R205G 		nuclear cataract J:195727
Gja8R205G/?
involves: CWD/LeAgl * SJL/J 		cataract J:156373
microphthalmia J:156373
Gja8R205G/Gja8R205G
B6.Cg-Gja8R205G 		lens vacuoles J:195727
microphthalmia J:195727
nuclear cataract J:195727
small lens J:195727
Gja8R205G/Gja8R205G
CWXS/Agl-Gja8R205G 		microphthalmia J:195727
nuclear cataract J:195727
Gja8R205G/Gja8R205G
involves: 129S4/SvJae * CWD/LeAgl * SJL/J 		abnormal lens fiber morphology J:195727
lens vacuoles J:195727
nuclear cataract J:195727
Gja8R205G/Gja8tm1Scr
involves: 129S1/Sv * 129X1/SvJ * CWD/LeAgl * SJL/J 		microphthalmia J:195727
nuclear cataract J:195727
Gja8tm1(Gja3)Tww/Gja8tm1(Gja3)Tww
involves: 129S/SvEv 		abnormal eye development J:73875
abnormal lens development J:73875
microphthalmia J:73875
small lens J:73875
Gja8tm1b(EUCOMM)Hmgu/Gja8tm1b(EUCOMM)Hmgu
C57BL/6N-Gja8tm1b(EUCOMM)Hmgu/H 		abnormal retina morphology J:211773
increased circulating amylase level J:211773
increased kidney weight J:211773
Gja8tm1Paul/Gja8tm1Paul
involves: 129S4/SvJae * C57BL/6J 		abnormal eye development J:50894
abnormal eye morphology J:50894
abnormal lens development J:50894
abnormal lens fiber morphology J:50894
cataract J:50894
microphthalmia J:50894
small lens J:50894
Gja8tm1Rtm/Gja8tm1Rtm
involves: 129/Sv * C57BL/6 		abnormal eye electrophysiology J:106299
abnormal eye physiology J:106299
abnormal lens morphology J:106299
cataract J:106299
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory