Jak3 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Jak3
Janus kinase 3
MGI:99928

18 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Crb1^rd8+em1Boc/Crb1^rd8+em1Boc Jak3^m1J/Jak3^m1J B6.Cg-Crb1^rd8+em1Boc Jak3^m1J/Boc	small spleen	J:265859
	small thymus	J:265859
	normal vision/eye phenotype	J:265859
Crb1^rd8/Crb1^rd8 Jak3^m1J/Jak3^m1J B6.Cg-Crb1^rd8 Jak3^m1J/BocJ	abnormal cone electrophysiology	J:265859
	abnormal electroretinogram waveform feature	J:265859
	abnormal eye electrophysiology	J:265859
	abnormal retina morphology	J:265859
	abnormal retina pigment epithelium morphology	J:265859
	abnormal retina pigmentation	J:265859
	abnormal retina vasculature morphology	J:265859
	abnormal rod electrophysiology	J:265859
	decreased spleen weight	J:265859
	retina neovascularization	J:265859
	retina spots	J:265859
	small spleen	J:265859
	small thymus	J:265859
Jak3^tm1Jni/Jak3^tm1Jni Crlf2^tm1Jni/Crlf2^tm1Jni involves: 129P2/OlaHsd * C57BL/6	abnormal B cell differentiation	J:89031
	decreased B cell number	J:89031
Jak3^tm1Ljb/Jak3^tm1Ljb Rag1^tm1Mom/Rag1^tm1Mom involves: 129S4/SvJae * 129S7/SvEvBrd	abnormal splenic cell ratio	J:56629
	normal immune system phenotype	J:56629
Jak3^X887Y/Jak3^X887Y Trdc^tm1Mal/Trdc^tm1Mal involves: C57BL/6	normal immune system phenotype	J:112658

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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