Tie1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tie1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
MGI:99906

19 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Tek^tm1Dmt/Tek⁺ Tie1^tm1Jpa/Tie1^tm1Jpa involves: 129S1/Sv * 129X1/SvJ * CD-1	abnormal cardiovascular development	J:54983
	abnormal heart development	J:54983
	abnormal vascular development	J:54983
	congestive heart failure	J:54983
	edema	J:54983
	embryonic lethality during organogenesis, complete penetrance	J:54983
	enlarged pericardium	J:54983
	heart hemorrhage	J:54983
	hemorrhage	J:54983
Tek^tm1Dmt/Tek^tm1Dmt Tie1^tm1Jpa/Tie1^tm1Jpa involves: 129S1/Sv * 129X1/SvJ * CD-1	abnormal blood vessel morphology	J:54983
	abnormal forebrain development	J:54983
	abnormal heart development	J:54983
	abnormal myocardial trabeculae morphology	J:54983
	abnormal somite development	J:54983
	abnormal vascular development	J:54983
	abnormal vitelline vascular remodeling	J:54983
	abnormal vitelline vasculature morphology	J:54983
	absent organized vascular network	J:54983
	congestive heart failure	J:54983
	decreased angiogenesis	J:54983
	decreased embryo size	J:54983
	edema	J:54983
	embryo tissue necrosis	J:54983
	embryonic lethality during organogenesis, complete penetrance	J:54983
	enlarged pericardium	J:54983

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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