Ryr2 Phenotype Annotations - Multigenic Genotypes

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ryr2
ryanodine receptor 2, cardiac
MGI:99685

4 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Ryr2^{tm1(CAG-KRASG12V,-lacZ)Nobs}/Ryr2^{tm1(CAG-KRASG12V,-lacZ)Nobs} Trp53^tm1Sia/Trp53⁺ involves: 129X1/SvJ * C57BL/6 * CBA	increased rhabdomyosarcoma incidence	J:117828
	increased tumor incidence	J:117828
Ryr2^{tm1(CAG-KRASG12V,-lacZ)Nobs}/Ryr2^{tm1(CAG-KRASG12V,-lacZ)Nobs} Trp53^tm1Sia/Trp53^tm1Sia involves: 129X1/SvJ * C57BL/6 * CBA	increased rhabdomyosarcoma incidence	J:117828
	increased tumor incidence	J:117828
	myositis	J:117828
Ryr2^tm2.1Wex/Ryr2^tm2.1Wex Tg(Myh6-EGFP/AC3I)#Mean/0 B6.Cg-Ryr2^tm2.1Wex Tg(Myh6-EGFP/AC3I)#Mean	ventricular tachycardia	J:179475

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/07/2024 MGI 6.23