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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Aldh2
aldehyde dehydrogenase 2, mitochondrial
MGI:99600
43 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Aldh2tm1a(EUCOMM)Wtsi/Aldh2+
Fancd2tm1Hou/Fancd2tm1Hou
involves: 129S4/SvJae * C57BL/6J * C57BL/6N
abnormal eye morphology J:193232
exencephaly J:193232
Aldh2tm1a(EUCOMM)Wtsi/Aldh2tm1a(EUCOMM)Wtsi
Fancd2tm1Hou/Fancd2+
involves: 129S4/SvJae * C57BL/6J * C57BL/6N
maternal effect J:193232
Aldh2tm1a(EUCOMM)Wtsi/Aldh2tm1a(EUCOMM)Wtsi
Fancd2tm1Hou/Fancd2tm1Hou
involves: 129S4/SvJae * C57BL/6J * C57BL/6N
abnormal bone marrow cell morphology/development J:193232
abnormal chest morphology J:193232
abnormal eye morphology J:193232
abnormal hematopoietic stem cell physiology J:188123
abnormal lymphopoiesis J:193232
abnormal spleen morphology J:188123
abnormal thymus morphology J:188123
anemia J:188123, J:193232
anophthalmia J:193232
decreased body weight J:193232
decreased bone marrow cell number J:188123, J:193232
decreased erythrocyte cell number J:188123, J:193232
decreased hematocrit J:188123
decreased hematopoietic stem cell number J:188123
decreased hemoglobin content J:188123, J:193232
decreased leukocyte cell number J:188123
embryonic lethality during organogenesis J:193232
enlarged spleen J:193232
exencephaly J:193232
extramedullary hematopoiesis J:188123
impaired hematopoiesis J:193232
increased acute lymphoblastic leukemia incidence J:193232
increased CD8-positive, alpha-beta T cell number J:193232
increased double-positive T cell number J:193232
increased lymphoma incidence J:193232
increased mean corpuscular volume J:188123
increased physiological sensitivity to xenobiotic J:188123
increased sensitivity to induced cell death J:188123
increased susceptibility to xenobiotic induced morbidity/mortality J:193232
increased T cell derived lymphoma incidence J:193232
kinked tail J:193232
lethargy J:193232
pancytopenia J:188123
premature death J:193232
thrombocytopenia J:188123
weight loss J:193232
Apoetm1Unc/Apoetm1Unc
Tg(EIF1AX-Aldh2*E487K)101Oht/Tg(EIF1AX-Aldh2*E487K)101Oht
B6.Cg-Apoetm1Unc Tg(EIF1AX-Aldh2*E487K)101Oht
impaired spatial learning J:137374
Tg(APPSWE)2576Kha/?
Tg(EIF1AX-Aldh2*E487K)101Oht/?
involves: C57BL/6 * SJL
abnormal object recognition memory J:219346
abnormal spatial working memory J:219346
amyloid beta deposits J:219346
astrocytosis J:219346
decreased body weight J:219346
premature death J:219346
tau protein deposits J:219346

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory