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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Mc4r
melanocortin 4 receptor
MGI:99457
9 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
\Htr2ctm1Knk/Y
\Mc4rtm1Lowl/\Mc4rtm1Lowl
involves: 129S4/SvJae * C57BL/6 		decreased body mass index J:142503
normal growth/size/body region phenotype J:142503
polyphagia J:142503
\Mc3rtm1Lvp/\Mc3rtm1Lvp
\Mc4rtm1Dhu/\Mc4rtm1Dhu
involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J 		increased body weight J:64365
\Mc4rtm1Dhu/\Mc4rtm1Dhu
\Pomctm1Low/\Pomctm1Low
involves: 129S2/SvPas * 129S4/SvJae * C57BL/6 		increased body weight J:115712
polyphagia J:115712
\Mc4rtm1Lowl/\Mc4r+
\Mrap2tm1.1Maj/\Mrap2+
involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 		obese J:199365
\Mc4rtm1Lowl/\Mc4rtm1Lowl
\Mrap2tm1.1Maj/\Mrap2tm1.1Maj
involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 		obese J:199365
\Mc4rtm2Lowl/\Mc4rtm2Lowl
\Chattm1(cre)Lowl/\Chat+
\Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/\Gt(ROSA)26Sor+
involves: 129S6/SvEvTac * C57BL/6NCr 		abnormal nervous system electrophysiology J:193452
normal nervous system phenotype J:193452
\Or8a1tm42(Mc4r)Mom/\Or8a1tm42(Mc4r)Mom
B6;129P2-Or8a1tm42(Mc4r)Mom/MomJ 		abnormal olfactory sensory neuron morphology J:260975
decreased olfactory sensory neuron number J:260975
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory