Mc4r Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mc4r
melanocortin 4 receptor
MGI:99457

9 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Htr2c^tm1Knk/Y Mc4r^tm1Lowl/Mc4r^tm1Lowl involves: 129S4/SvJae * C57BL/6	decreased body mass index	J:142503
	normal growth/size/body region phenotype	J:142503
	polyphagia	J:142503
Mc3r^tm1Lvp/Mc3r^tm1Lvp Mc4r^tm1Dhu/Mc4r^tm1Dhu involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J	increased body weight	J:64365
Mc4r^tm1Dhu/Mc4r^tm1Dhu Pomc^tm1Low/Pomc^tm1Low involves: 129S2/SvPas * 129S4/SvJae * C57BL/6	increased body weight	J:115712
	polyphagia	J:115712
Mc4r^tm1Lowl/Mc4r⁺ Mrap2^tm1.1Maj/Mrap2⁺ involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6	obese	J:199365
Mc4r^tm1Lowl/Mc4r^tm1Lowl Mrap2^tm1.1Maj/Mrap2^tm1.1Maj involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6	obese	J:199365
Mc4r^tm2Lowl/Mc4r^tm2Lowl Chat^tm1(cre)Lowl/Chat⁺ Gt(ROSA)26Sor^{tm14(CAG-tdTomato)Hze}/Gt(ROSA)26Sor⁺ involves: 129S6/SvEvTac * C57BL/6NCr	abnormal nervous system electrophysiology	J:193452
	normal nervous system phenotype	J:193452
Or8a1^{tm42(Mc4r)Mom}/Or8a1^{tm42(Mc4r)Mom} B6;129P2-Or8a1^{tm42(Mc4r)Mom}/MomJ	abnormal olfactory sensory neuron morphology	J:260975
	decreased olfactory sensory neuron number	J:260975

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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