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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Btc
betacellulin, epidermal growth factor family member
MGI:99439
45 phenotypes from 4 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Btcem1(IMPC)Mbp/Btcem1(IMPC)Mbp
C57BL/6N-Btcem1(IMPC)Mbp/MbpMmucd 		abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
increased neutrophil cell number J:211773
Btctm1Dcl/Btctm1Dcl
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J 		no abnormal phenotype detected J:83820
Tg(CAG-Btc)2Ewo/0
FVB/N-Tg(CAG-Btc)2Ewo 		abnormal atrioventricular valve morphology J:103364
abnormal cranium morphology J:103364
abnormal eye morphology J:103364
abnormal lens fiber morphology J:103364
abnormal lens morphology J:103364
abnormal lung morphology J:103364
abnormal pulmonary alveolus morphology J:103364
abnormal retina ganglion layer morphology J:103364
abnormal retina inner nuclear layer morphology J:103364
abnormal retina layer morphology J:103364
abnormal retina morphology J:103364
abnormal skeleton development J:103364
cardiac hypertrophy J:103364
cataract J:103364
cyanosis J:103364
decreased body length J:103364
decreased body size J:103364
decreased cranium height J:103364
decreased pancreas weight J:103364
decreased total retina thickness J:103364
domed cranium J:103364
enlarged heart J:103364
globular heart J:103364
heart left ventricle hypertrophy J:103364
heart right ventricle hypertrophy J:103364
increased cranium width J:103364
increased heart weight J:103364
increased liver weight J:103364
increased lung weight J:103364
increased ovary weight J:103364
increased spleen weight J:103364
overexpanded pulmonary alveolus J:103364
postnatal lethality, incomplete penetrance J:103364
pulmonary alveolar hemorrhage J:103364
respiratory distress J:103364
short nasal bone J:103364
slow postnatal weight gain J:103364
thick mitral valve J:103364
thick pulmonary interalveolar septum J:103364
thin retina inner nuclear layer J:103364
Tg(CAG-Btc)4Ewo/0
FVB/N-Tg(CAG-Btc)4Ewo 		abnormal atrioventricular valve morphology J:103364
abnormal eye morphology J:103364
abnormal lung morphology J:103364
abnormal pulmonary alveolus morphology J:103364
cyanosis J:103364
decreased body length J:103364
decreased body size J:103364
decreased body weight J:103364
decreased pancreas weight J:103364
enlarged heart J:103364
globular heart J:103364
heart left ventricle hypertrophy J:103364
heart right ventricle hypertrophy J:103364
increased heart weight J:103364
increased liver weight J:103364
increased lung weight J:103364
increased ovary weight J:103364
increased spleen weight J:103364
overexpanded pulmonary alveolus J:103364
postnatal lethality, incomplete penetrance J:103364
pulmonary alveolar hemorrhage J:103364
respiratory distress J:103364
thick mitral valve J:103364
thick pulmonary interalveolar septum J:103364
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory