Uros Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Uros
uroporphyrinogen III synthase
MGI:98917

35 phenotypes from 6 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Uros^tm1Cged/Uros^tm1Cged involves: 129S2/SvPas	abnormal proximal convoluted tubule morphology	J:105776
	abnormal renal glomerulus morphology	J:105776
	abnormal renal tubule morphology	J:105776
	abnormal skeleton morphology	J:105776
	anisocytosis	J:105776
	decreased birth body size	J:105776
	enlarged liver	J:105776
	enlarged spleen	J:105776
	erythrodontia	J:105776
	erythruria	J:105776
	fragile skeleton	J:105776
	hemolytic anemia	J:105776
	hepatic steatosis	J:105776
	hypochromic microcytic anemia	J:105776
	increased bone marrow cell number	J:105776
	increased spleen red pulp amount	J:105776
	poikilocytosis	J:105776
	porphyria	J:105776
	skin photosensitivity	J:105776
Uros^tm1Rjde/Uros^tm1Rjde involves: 129S6/SvEvTac * C57BL/6	preweaning lethality, complete penetrance	J:132542
Uros^tm1Rjde/Uros^tm3Rjde involves: 129S6/SvEvTac * C57BL/6	increased porphyrin level	J:132542
Uros^tm2Cged/Uros^tm2Cged involves: 129S2/SvPas	embryonic lethality before implantation, complete penetrance	J:107043
Uros^tm2Rjde/Uros^tm2Rjde involves: 129S6/SvEvTac * C57BL/6	preweaning lethality, complete penetrance	J:132542
Uros^tm2Rjde/Uros^tm3Rjde involves: 129S6/SvEvTac * C57BL/6	abnormal enzyme/coenzyme activity	J:132542
	abnormal erythropoiesis	J:132542
	decreased circulating haptoglobin level	J:132542
	enlarged spleen	J:132542
	normal hematopoietic system phenotype	J:132542
	hemolysis	J:132542
	hemolytic anemia	J:132542
	increased porphyrin level	J:132542
	increased spleen iron level	J:132542
	reticulocytosis	J:132542
Uros^tm2Rjde/Uros^tm3Rjde involves: 129S6/SvEvTac * C57BL/6 * SKH1	abnormal dermal layer morphology	J:132542
	abnormal dermis papillary layer morphology	J:132542
	acanthosis	J:132542
	increased porphyrin level	J:132542
	mixed cellular infiltration to dermis	J:132542
	skin photosensitivity	J:132542
	thick skin	J:132542
Uros^tm3Rjde/Uros^tm3Rjde involves: 129S6/SvEvTac * C57BL/6	abnormal enzyme/coenzyme activity	J:132542
	normal hematopoietic system phenotype	J:132542
	increased porphyrin level	J:132542
Uros^tm3Rjde/Uros^tm3Rjde involves: 129S6/SvEvTac * C57BL/6 * SKH1	increased porphyrin level	J:132542
	skin photosensitivity	J:132542
	thick epidermis	J:132542
Uros^tm3Rjde/Uros^tm4Rjde involves: 129S6/SvEvTac * C57BL/6	increased porphyrin level	J:132542
Uros^tm4Rjde/Uros^tm4Rjde involves: 129S6/SvEvTac * C57BL/6	preweaning lethality, complete penetrance	J:132542

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