Tgm2 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tgm2
transglutaminase 2, C polypeptide
MGI:98731

10 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Abca1^tm1Jdm/Abca1^tm1Jdm Tgm2^tm1Gml/Tgm2^tm1Gml involves: C57BL/6 * DBA/1LacJ	abnormal thymus morphology	J:132254
	decreased circulating cholesterol level	J:132254
	decreased circulating HDL cholesterol level	J:132254
	normal homeostasis/metabolism phenotype	J:132254
	impaired macrophage phagocytosis	J:132254
	perinatal lethality	J:132254
Tgm2^tm1.1Rmgr/Tgm2⁺ Tg(HDexon1)62Gpb/0 involves: 129X1/SvJ * C57BL/6 * CBA	abnormal cerebral cortex morphology	J:95452
	abnormal striatum morphology	J:95452
Tgm2^tm1.1Rmgr/Tgm2^tm1.1Rmgr Tg(HDexon1)62Gpb/0 involves: 129X1/SvJ * C57BL/6 * CBA	abnormal cerebral cortex morphology	J:95452
	abnormal striatum morphology	J:95452
	extended life span	J:95452
	impaired coordination	J:95452

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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