Sptan1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sptan1
spectrin alpha, non-erythrocytic 1
MGI:98386

40 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sptan1^em1(IMPC)Mbp/Sptan1⁺ C57BL/6NCrl-Sptan1^em1(IMPC)Mbp/MbpMmucd	abnormal eye morphology	J:211773
	abnormal kidney morphology	J:211773
	abnormal placenta morphology	J:211773
	abnormal retina vasculature morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal vitreous body morphology	J:211773
	cataract	J:211773
	decreased body length	J:211773
	enlarged kidney	J:211773
	enlarged spleen	J:211773
	microphthalmia	J:211773
	persistence of hyaloid vascular system	J:211773
Sptan1^em1(IMPC)Mbp/Sptan1^em1(IMPC)Mbp C57BL/6NCrl-Sptan1^em1(IMPC)Mbp/MbpMmucd	abnormal craniofacial morphology	J:211773
	abnormal forebrain development	J:211773
	abnormal head shape	J:211773
	abnormal midbrain development	J:211773
	abnormal neural tube closure	J:211773
	abnormal neural tube morphology	J:211773
	abnormal placenta morphology	J:211773
	abnormal visceral yolk sac morphology	J:211773
	edema	J:211773
	embryonic growth retardation	J:211773
	microcephaly	J:211773
	preweaning lethality, complete penetrance	J:211773
Sptan1^{Gt(RRQ171)Byg}/Sptan1^{Gt(RRQ171)Byg} B6.129P2-Sptan1^{Gt(RRQ171)Byg}	abnormal cell physiology	J:186305
	abnormal cortical ventricular zone morphology	J:186305
	abnormal craniofacial morphology	J:186305
	abnormal embryonic/fetal subventricular zone morphology	J:186305
	abnormal forebrain morphology	J:186305
	abnormal heart shape	J:186305
	abnormal lateral ventricle morphology	J:186305
	abnormal neural tube closure	J:186305
	cerebral aqueductal stenosis	J:186305
	decreased embryo size	J:186305
	dilated brain ventricle	J:186305
	dilated heart	J:186305
	embryonic growth retardation	J:186305
	embryonic lethality during organogenesis, incomplete penetrance	J:186305
	increased cell proliferation	J:186305
	lethality throughout fetal growth and development, complete penetrance	J:186305
	thin myocardium compact layer	J:186305
Sptan1^{Gt(RRQ171)Byg}/Sptan1^{Gt(RRQ171)Byg} involves: 129P2/OlaHsd	abnormal axon initial segment morphology	J:186168
Sptan1^tm1.1Gnic/Sptan1^tm1.1Gnic either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6)	normal cellular phenotype	J:122549
	no abnormal phenotype detected	J:122549

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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