Serpina1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Serpina1
serine (or cysteine) peptidase inhibitor, clade A, member 1 cluster
MGI:98376

10 phenotypes from 4 alleles in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
Serpina1^em1Chmu/Serpina1^em1Chmu involves: C57BL/6J	emphysema	J:259615
Serpina1^em2Chmu/Serpina1^em2Chmu involves: C57BL/6J	emphysema	J:259615
Serpina1^em3Chmu/Serpina1^em3Chmu involves: C57BL/6J	emphysema	J:259615
Serpina1^em#Chmu/Serpina1^em#Chmu involves: C57BL/6J	abnormal enzyme/coenzyme activity	J:259615
	abnormal inspiratory capacity	J:259615
	abnormal lung volume	J:259615
	decreased lung elastance	J:259615
	dilated pulmonary alveolar duct	J:259615
	emphysema	J:259615
	increased lung compliance	J:259615
	increased susceptibility to endotoxin shock	J:259615
	overexpanded pulmonary alveolus	J:259615
	respiratory system inflammation	J:259615

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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