Msr1 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Msr1
macrophage scavenger receptor 1
MGI:98257

8 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
\Apoe^tm1Unc/\Apoe^tm1Unc \Msr1^tm1Csk/\Msr1^tm1Csk either: (involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6J * ICR) or (involves: 129P2/OlaHsd * 129X1/SvJ * 129/Sv * ICR)	atherosclerotic lesions	J:39079
	increased circulating cholesterol level	J:39079
\Marco^tm1Ktry/\Marco^tm1Ktry \Msr1^tm1Csk/\Msr1^tm1Csk B6.129-Marco^tm1Ktry Msr1^tm1Csk	abnormal macrophage physiology	J:122271
	abnormal spleen marginal zone morphology	J:122271
	increased IgM level	J:122271
	increased susceptibility to bacterial infection	J:122271
\Msr1^tm1Csk/\Msr1^tm1Csk \Scarf1^tm1Ishi/\Scarf1^tm1Ishi involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6J	abnormal macrophage physiology	J:91911
\Msr1^tm1Csk/\Msr1^tm1Csk \Tg(APPV717F)109Ili/? involves: 129X1/SvJ * C57BL/6 * DBA/2 * ICR	amyloid beta deposits	J:58338
	neuron degeneration	J:58338

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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