Ren1 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ren1
renin 1 structural
MGI:97898

14 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Adm^tm1Unc/Adm⁺ Tg(Alb1-Ren)2Unc/? 129S6/SvEvTac-Adm^tm1Unc Tg(Alb1-Ren)2Unc	cardiac hypertrophy	J:125933
	glomerulosclerosis	J:125933
	increased myocardial fiber size	J:125933
	increased systemic arterial blood pressure	J:125933
	renal cast	J:125933
	renal fibrosis	J:125933
Gnas^tm3Lsw/Gnas^tm3Lsw Ren1^tm2(cre)Gom/Ren1⁺ involves: 129S6/SvEvTac * Black Swiss	abnormal kidney physiology	J:118076
	abnormal renin activity	J:118076
	decreased circulating aldosterone level	J:118076
	decreased circulating renin level	J:118076
	decreased mean systemic arterial blood pressure	J:118076
	decreased renal glomerular filtration rate	J:118076
	decreased urine osmolality	J:118076
	increased urine prostaglandin level	J:118076

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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