Eprs1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Eprs1
glutamyl-prolyl-tRNA synthetase 1
MGI:97838

23 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Eprs1^tm1.1Xen/Eprs1^tm1.1Xen C57BL/6-Eprs1^tm1.1Xen	abnormal adipose tissue physiology	J:244749
	decreased abdominal adipose tissue amount	J:244749
	decreased body weight	J:244749
	decreased brown adipose tissue amount	J:244749
	decreased susceptibility to diet-induced obesity	J:244749
	decreased white fat cell size	J:244749
	enhanced lipolysis	J:244749
	extended life span	J:244749
	normal homeostasis/metabolism phenotype	J:244749
	impaired glucose tolerance	J:244749
	increased carbon dioxide production	J:244749
	increased energy expenditure	J:244749
	increased fatty acid beta-oxidation	J:244749
	increased insulin sensitivity	J:244749
	increased oxygen consumption	J:244749
Eprs1^{tm1b(EUCOMM)Hmgu}/Eprs1⁺ C57BL/6N-Eprs1^{tm1b(EUCOMM)Hmgu}/Tcp	abnormal embryo size	J:211773
	abnormal lung morphology	J:211773
	decreased circulating creatinine level	J:211773
	decreased prepulse inhibition	J:211773
Eprs1^{tm1b(EUCOMM)Hmgu}/Eprs1^{tm1b(EUCOMM)Hmgu} C57BL/6N-Eprs1^{tm1b(EUCOMM)Hmgu}/Tcp	embryonic lethality prior to organogenesis	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773
Eprs1^tm2.1Xen/Eprs1^tm2.1Xen C57BL/6-Eprs1^tm2.1Xen	no abnormal phenotype detected	J:244749

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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