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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Plcg2
phospholipase C, gamma 2
MGI:97616
22 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Blnktm1Kplm/Blnktm1Kplm
Plcg2tm1.1Kuro/Plcg2+
involves: 129P2/OlaHsd
abnormal B cell activation J:131161
decreased B cell number J:131161
increased B cell apoptosis J:131161
Blnktm1Kplm/Blnktm1Kplm
Plcg2tm1.1Kuro/Plcg2tm1.1Kuro
involves: 129P2/OlaHsd
decreased B cell number J:131161
increased B cell apoptosis J:131161
perinatal lethality, incomplete penetrance J:131161
spleen hypoplasia J:131161
Ightm1.1Twin/Ightm1.1Twin
Plcg2Ali5/Plcg2+
involves: 129 * 129S4/SvJae * C3HeB/FeJ * C57BL/6
normal immune system phenotype J:174233
increased B-1a cell number J:174233
Pik3r1tm1Dfr/Pik3r1tm1Dfr
Plcg2tm1Jni/Plcg2tm1Jni
involves: 129P2/OlaHsd * 129S6/SvEvTac
abnormal B cell differentiation J:104166
arrested B cell differentiation J:104166
decreased body size J:104166
decreased immature B cell number J:104166
decreased mature B cell number J:104166
decreased pre-B cell number J:104166
normal hematopoietic system phenotype J:104166
normal immune system phenotype J:104166
increased B cell apoptosis J:104166
lethality throughout fetal growth and development, complete penetrance J:104166
Plcg2Ali5/Plcg2+
Rag1tm1Mom/Rag1tm1Mom
involves: 129S7/SvEvBrd * C3HeB/FeJ * C3HeB/FeJ-Plcg2Ali5
chronic inflammation J:97930
dermatitis J:97930
osteoarthritis J:97930
Plcg2tm1Jni/Plcg2tm1Jni
Tg(IghMyc)22Bri/0
involves: 129P2/OlaHsd * C57BL * C57BL/6 * SJL
enlarged lymph nodes J:117023
increased B cell derived lymphoma incidence J:117023
increased lymphoma incidence J:117023
premature death J:117023

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory