Prkca Phenotype Annotations

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Prkca
protein kinase C, alpha
MGI:97595

13 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Prkca^tm1Cda/Prkca^tm1Cda involves: 129S/SvEv * C57BL/6	epidermal hyperplasia	J:100793
Prkca^tm1Cda/Prkca^tm1Cda involves: 129S/SvEv * C57BL/6	increased skin papilloma incidence	J:100793
Prkca^tm1Far/Prkca^tm1Far involves: 129/Sv * 129P2/OlaHsd	abnormal enzyme/coenzyme activity	J:85923
	normal homeostasis/metabolism phenotype	J:85923
	increased adipocyte glucose uptake	J:85923
	increased muscle cell glucose uptake	J:85923
Prkca^tm1Far/Prkca^tm1Far involves: 129P2/OlaHsd	normal nervous system phenotype	J:159855
Prkca^tm1Jmk/Prkca^tm1Jmk involves: 129	abnormal cardiac muscle contractility	J:132098
	abnormal myocardium layer morphology	J:132098
	normal cardiovascular system phenotype	J:88510, J:132098
	decreased response of heart to induced stress	J:88510
Tg(Myh6-Prkca)1Jmk/0 involves: FVB	cardiac hypertrophy	J:88510
Tg(Myh6-Prkca)1Jmk/0 involves: FVB	decreased cardiac muscle contractility	J:88510

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23