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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Abcb1a
ATP-binding cassette, sub-family B member 1A
MGI:97570
32 phenotypes from 2 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Abcb1amds/Abcb1amds
involves: CF-1
abnormal hippocampus CA3 region morphology J:64725
catalepsy J:64725
hippocampal neuron degeneration J:64725
increased eosinophil cell number J:64725
increased physiological sensitivity to xenobiotic J:40292, J:64725
premature death J:64725
tremors J:64725
Abcb1atm1Bor/Abcb1atm1Bor
FVB.129P2-Abcb1atm1Bor/TacImx
abnormal intestinal epithelium morphology J:51190
abnormal intestinal mucosa morphology J:51190
abnormal large intestine crypts of Lieberkuhn morphology J:51190
abnormal lymphocyte physiology J:51190
cachexia J:51190
colitis J:51190
crypts of Lieberkuhn abscesses J:51190
increased IgA level J:51190
increased IgE level J:51190
increased IgG1 level J:51190
increased IgG2 level J:51190
increased IgG2a level J:51190
increased IgG2b level J:51190
increased IgG3 level J:51190
increased IgM level J:51190
increased immunoglobulin level J:51190
intestinal ulcer J:51190
large intestinal inflammation J:51190
mucous diarrhea J:51190
Abcb1atm1Bor/Abcb1atm1Bor
FVBTac.129P2-Abcb1atm1Bor
abnormal blood-inner ear barrier function J:59145
abnormal CD8 positive, alpha-beta intraepithelial T cell morphology J:102640
abnormal xenobiotic pharmacokinetics J:59145, J:102640
decreased gamma-delta intraepithelial T cell number J:102640
increased physiological sensitivity to xenobiotic J:59145
increased susceptibility to ototoxicity-induced hearing loss J:59145
Abcb1atm1Bor/Abcb1atm1Bor
involves: 129P2/OlaHsd * FVB
abnormal xenobiotic pharmacokinetics J:39804
impaired blood-brain barrier function J:18554
increased physiological sensitivity to xenobiotic J:18554

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory