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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pgam1
phosphoglycerate mutase 1
MGI:97552
17 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Pgam1tm1.1Hiko/Pgam1tm1.1Hiko
Tg(Cd4-cre)1Cwi/0
involves: C57BL/6 * DBA/2 		abnormal CD4-positive T cell differentiation J:293746
abnormal CD8-positive, alpha-beta T cell differentiation J:293746
abnormal effector T cell number J:293746
abnormal metabolism J:293746
abnormal nucleotide metabolism J:293746
abnormal pH regulation J:293746
decreased acute inflammation J:293746
decreased CD4-positive, alpha-beta T cell number J:293746
decreased CD8-positive, alpha-beta T cell number J:293746
decreased interleukin-2 secretion J:293746
decreased NK T cell number J:293746
decreased oxygen consumption J:293746
decreased susceptibility to experimental autoimmune encephalomyelitis J:293746
decreased T-helper 2 cell number J:293746
decreased T-helper 17 cell number J:293746
normal hematopoietic system phenotype J:293746
Pgam1tm2.2Hiko/Pgam1tm2.2Hiko
involves: C57BL/6 		embryonic lethality, complete penetrance J:307317
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory