Pfn1 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pfn1
profilin 1
MGI:97549

9 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Enah^tm1Fbg/Enah^tm1Fbg Pfn1^tm1Wit/Pfn1⁺ involves: 129S4/SvJae	anencephaly	J:53259
	decreased embryo size	J:53259
	exencephaly	J:53259
	incomplete rostral neuropore closure	J:53259
	perinatal lethality, complete penetrance	J:53259
Ldlr^tm1Her/Ldlr^tm1Her Pfn1^tm1Wit/Pfn1⁺ B6.129S-Ldlr^tm1Her Pfn1^tm1Wit	atherosclerotic lesions	J:140294
	impaired macrophage chemotaxis	J:140294
	prenatal lethality, incomplete penetrance	J:140294
Pfn1^{tm2.1(GFP/ACTB)Wit}/Pfn1^{tm2.1(GFP/ACTB)Wit} involves: 129S4/SvJae * BALB/cJ	lethality, complete penetrance	J:209786

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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