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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Pdyn
prodynorphin
MGI:97535
30 phenotypes from 4 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Pdynem1(IMPC)Rbrc/Pdynem1(IMPC)Rbrc
C57BL/6NJcl-Pdynem1(IMPC)Rbrc/Rbrc
abnormal circulating iron level J:211773
abnormal platelet cell number J:211773
Pdyntm1(cre)Czer/Pdyn+
B6.Cg-Pdyntm1(cre)Czer
increased susceptibility to pharmacologically induced seizures J:122651
Pdyntm1(cre)Czer/Pdyntm1(cre)Czer
B6.Cg-Pdyntm1(cre)Czer
abnormal brain interneuron morphology J:122651
abnormal cerebellar granule cell morphology J:122651
increased susceptibility to pharmacologically induced seizures J:122651
Pdyntm1(cre)Czer/Pdyntm1(cre)Czer
involves: 129X1/SvJ * C57BL/6
abnormal eating behavior J:122399
abnormal homeostasis J:122399
abnormal response/metabolism to endogenous compounds J:122399
decreased abdominal adipose tissue amount J:122399
decreased body temperature J:122399
decreased circulating glucagon level J:122399
decreased circulating glucose level J:122399
decreased circulating insulin-like growth factor I level J:122399
decreased circulating thyroxine level J:122399
decreased lean body mass J:122399
decreased locomotor activity J:122399
decreased respiratory quotient J:122399
decreased subcutaneous adipose tissue amount J:122399
decreased white adipose tissue amount J:122399
increased bone mineral content J:122399
increased circulating corticosterone level J:122399
increased defecation amount J:122399
weight loss J:122399
Pdyntm1Ute/Pdyntm1Ute
B6.129S4-Pdyntm1Ute
abnormal anxiety-related response J:84344
decreased anxiety-related response J:84344
impaired conditioned place preference behavior J:84344
Pdyntm1Ute/Pdyntm1Ute
involves: 129S4/SvJae * 129S6/SvEvTac
abnormal response to tactile stimuli J:67584
abnormal thermal nociception J:67584
abnormal touch/ nociception J:67584
Pdyntm1Zim/Pdyntm1Zim
involves: 129/Sv * C57BL/6
decreased chemically-elicited antinociception J:123424
impaired conditioned place preference behavior J:123424

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory