Pdyn^tm1Ute
Targeted Allele Detail

Summary

• Symbol: Pdyn^tm1Ute
• Name: prodynorphin; targeted mutation 1, Ute Hochgeschwender
• MGI ID: MGI:2176368
• Synonyms: Dyn^-, Dyn^tm3Ute, Pdyn-
• Gene: Pdyn Location: Chr2:129528485-129541764 bp, - strand Genetic Position: Chr2, 63.19 cM
• Alliance: Pdyn^tm1Ute page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:67203
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A genomic fragment containing exon 3 and part of exon 4 was replaced with a neomycin selection cassette. The deleted sequences include all of the coding region. (J:67203)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pdyn Mutation: 19 strains or lines available

References

• Original: J:67203 Sharifi N, et al., Generation of dynorphin knockout mice. Brain Res Mol Brain Res. 2001 Jan 31;86(1-2):70-5
• All: 24 reference(s)