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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Pbx3
pre B cell leukemia homeobox 3
MGI:97496
32 phenotypes from 5 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Hoxb1tm1(cre)Og/Hoxb1+
Pbx3tm1Og/Pbx3tm1Og
involves: 129S/SvEv * 129S4/SvJae * C57BL/6
abnormal behavior J:130927
abnormal limb posture J:130927
abnormal locomotor coordination J:130927
abnormal neuron differentiation J:130927
abnormal neuron morphology J:130927
abnormal spinal cord dorsal horn morphology J:130927
bradykinesia J:130927
decreased body size J:130927
decreased neuron number J:130927
decreased thermal nociceptive threshold J:130927
hyporesponsive to tactile stimuli J:130927
impaired coordination J:130927
improved righting response J:130927
increased startle reflex J:130927
limb grasping J:130927
Pbx3tm1.1Og/Pbx3tm1.1Og
involves: 129S4/SvJae * C57BL/6
cyanosis J:130927
neonatal lethality, complete penetrance J:130927
Pbx3tm1a(EUCOMM)Wtsi/Pbx3+
Not Specified
abnormal response to new environment J:165965
Pbx3tm1a(EUCOMM)Wtsi/Pbx3tm1a(EUCOMM)Wtsi
Not Specified
decreased bone mineral density J:165965
decreased circulating cholesterol level J:165965
increased bone mineral density J:165965
increased circulating cholesterol level J:165965
increased lean body mass J:165965
Pbx3tm1b(EUCOMM)Wtsi/Pbx3+
C57BL/6N-Pbx3tm1b(EUCOMM)Wtsi/H
abnormal tooth morphology J:211773
absent ovary J:211773
decreased blood urea nitrogen level J:211773
decreased total body fat amount J:211773
increased circulating bilirubin level J:211773
Pbx3tm1b(EUCOMM)Wtsi/Pbx3tm1b(EUCOMM)Wtsi
C57BL/6N-Pbx3tm1b(EUCOMM)Wtsi/H
preweaning lethality, complete penetrance J:211773
Pbx3tm1Mlc/Pbx3tm1Mlc
involves: C57BL/6
abnormal somatic nervous system physiology J:93761
cyanosis J:93761
hypoventilation J:93761
neonatal lethality, complete penetrance J:93761
respiratory failure J:93761

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory