65 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Atad3atm1c(KOMP)Wtsi/Atad3atm1c(KOMP)Wtsi Myl1tm1(cre)Sjb/Myl1+ B6J.Cg-Myl1tm1(cre)Sjb Atad3atm1c(KOMP)Wtsi	abnormal cholesterol homeostasis	J:263681
	abnormal mitochondrial crista morphology	J:263681
	abnormal motor coordination/balance	J:263681
	abnormal muscle fiber mitochondrial morphology	J:263681
	abnormal muscle fiber morphology	J:263681
	abnormal oxidative phosphorylation	J:263681
	cachexia	J:263681
	decreased grip strength	J:263681
	decreased locomotor activity	J:263681
	decreased mitochondrial size	J:263681
	decreased skeletal muscle fiber mitochondrial DNA content	J:263681
	decreased skeletal muscle weight	J:263681
	disorganized mitochondrial cristae	J:263681
	normal growth/size/body region phenotype	J:263681
	kyphosis	J:263681
	skeletal muscle fiber atrophy	J:263681
	skeletal muscle fiber degeneration	J:263681
	weakness	J:263681
Cox10tm1Ctm/Cox10tm1Ctm Myl1tm1(cre)Sjb/Myl1+ involves: 129X1/SvJ * C57BL/6	abnormal skeletal muscle morphology	J:101747
	decreased locomotor activity	J:101747
	decreased skeletal muscle mass	J:101747
	increased muscle fatigability	J:101747
	increased variability of skeletal muscle fiber size	J:101747
	kyphosis	J:101747
	myopathy	J:101747
	premature death	J:101747
	weight loss	J:101747
Hprt1tm1(CAG-Gys1*)Jjg/? Myl1tm1(cre)Sjb/Myl1+ involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ	abnormal cellular respiration	J:244440
	abnormal response to exercise	J:244440
	decreased aerobic running capacity	J:244440
	impaired exercise endurance	J:244440
	increased skeletal muscle glycogen level	J:244440
Myl1tm1(cre)Sjb/Myl1+ Tfamtm1Lrsn/Tfamtm1Lrsn involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal respiratory electron transport chain	J:81561
	bradykinesia	J:81561
	impaired skeletal muscle contractility	J:81561
	increased skeletal muscle fiber size	J:81561
	premature death	J:81561
	weight loss	J:81561
Myl1tm1(cre)Sjb/Myl1+ Shc1tm3Paw/Shc1tm9Paw involves: 129S1/Sv * 129X1/SvJ	abnormal locomotor coordination	J:122927
	decreased muscle spindle number	J:122927
	impaired limb coordination	J:122927
Myl1tm1(cre)Sjb/Myl1+ Shc1tm4Paw/Shc1tm9Paw involves: 129S1/Sv * 129X1/SvJ	abnormal locomotor coordination	J:122927
	abnormal muscle spindle morphology	J:122927
	ataxia	J:122927
Myl1tm1(cre)Sjb/Myl1+ Shc1tm7Paw/Shc1tm9Paw involves: 129S1/Sv * 129X1/SvJ	abnormal locomotor coordination	J:122927
	ataxia	J:122927
	decreased muscle spindle number	J:122927
	impaired limb coordination	J:122927
Myl1tm1(cre)Sjb/Myl1+ Shc1tm9Paw/Shc1tm9Paw involves: 129S1/Sv * 129X1/SvJ	abnormal locomotor coordination	J:122927
	ataxia	J:122927
	decreased muscle spindle number	J:122927
	impaired limb coordination	J:122927
Myl1tm1(cre)Sjb/Myl1+ Smarcd3tm1Jddl/Smarcd3tm1Jddl involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal muscle physiology	J:256788
	normal growth/size/body region phenotype	J:256788
	impaired glucose tolerance	J:256788
	increased circulating glucose level	J:256788
	insulin resistance	J:256788
Myl1tm1(cre)Sjb/0 Ndufab1tm1Xiwa/Ndufab1tm1Xiwa involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6	decreased body size	J:293657
	decreased circulating insulin level	J:293657
	decreased liver glycogen level	J:293657
	decreased skeletal muscle glycogen level	J:293657
	disorganized mitochondrial cristae	J:293657
	normal homeostasis/metabolism phenotype	J:293657
	hypoglycemia	J:293657
	normal muscle phenotype	J:293657
	postnatal growth retardation	J:293657
	preweaning lethality, complete penetrance	J:293657
Ralgapa1tm2c(KOMP)Wtsi/Ralgapa1tm2c(KOMP)Wtsi Myl1tm1(cre)Sjb/Myl1+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * C57BL/6N	abnormal lipid homeostasis	J:287672
	improved glucose tolerance	J:287672
	increased circulating cholesterol level	J:287672
	increased circulating free fatty acids level	J:287672
	increased circulating insulin level	J:287672
	increased circulating triglyceride level	J:287672
	increased muscle cell glucose uptake	J:287672
Trp53inp2tm1Azo/Trp53inp2tm1Azo Myl1tm1(cre)Sjb/Myl1+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal skeletal muscle morphology	J:212763
	decreased physiological sensitivity to xenobiotic	J:212763
	normal homeostasis/metabolism phenotype	J:212763
	impaired autophagy	J:212763
	increased lean body mass	J:212763
	increased skeletal muscle fiber diameter	J:212763
	increased skeletal muscle weight	J:212763
	skeletal muscle hypertrophy	J:212763