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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Blnk
B cell linker
MGI:96878
45 phenotypes from 6 alleles in 8 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Blnkem1(IMPC)H/Blnkem1(IMPC)H
C57BL/6N-Blnkem1(IMPC)H/H
decreased basophil cell number J:211773
decreased large unstained cell number J:211773
decreased leukocyte cell number J:211773
decreased lymphocyte cell number J:211773
decreased spleen weight J:211773
increased eosinophil cell number J:211773
increased neutrophil cell number J:211773
small spleen J:211773
Blnkm1Btlr/Blnkm1Btlr
C57BL/6J-Blnkm1Btlr
arrested B cell differentiation J:159439
decreased IgG level J:159439
decreased IgM level J:159439
decreased mature B cell number J:159439
increased CD4-positive, alpha-beta T cell number J:159439
increased CD8-positive, alpha-beta T cell number J:159439
Blnkm1Btlr/Blnkm1Btlr
involves: C57BL/6J
arrested B cell differentiation J:185495
decreased IgM level J:185495
normal immune system phenotype J:185495
Blnktm1Achn/Blnk+
involves: 129S4/SvJae * 129X1/SvJ * BALB/c * C3H * C57BL/6
decreased B cell proliferation J:82430
Blnktm1Achn/Blnktm1Achn
involves: 129X1/SvJ
abnormal B cell differentiation J:58805
abnormal mature B cell morphology J:58805
absent B-1b cells J:58805
arrested B cell differentiation J:58805
normal cardiovascular system phenotype J:58805
decreased B-1a cell number J:58805
decreased immunoglobulin level J:58805
decreased mature B cell number J:58805
decreased splenocyte number J:58805
increased pro-B cell number J:58805
Blnktm1Dkit/Blnktm1Dkit
involves: C57BL/6
abnormal B cell apoptosis J:143854
abnormal B cell differentiation J:84040
abnormal immature B cell morphology J:94297
abnormal plasma cell differentiation J:143854
abnormal pre-B cell morphology J:84040
arrested B cell differentiation J:143854
decreased follicular B cell number J:143854
decreased IgG3 level J:143854
decreased IgM level J:143854
decreased immature B cell number J:84040
decreased marginal zone B cell number J:143854
decreased mature B cell number J:84040
decreased transitional stage B cell number J:143854
increased anti-double stranded DNA antibody level J:94297
increased B cell apoptosis J:143854
increased leukemia incidence J:84040
Blnktm1Kplm/Blnktm1Kplm
involves: 129P2/OlaHsd
abnormal B cell activation J:61130, J:131161
abnormal B cell differentiation J:61130, J:131161
absent B-1a cells J:61130
decreased B cell number J:61130, J:131161
decreased B cell proliferation J:61130
decreased immature B cell number J:61130
decreased mature B cell number J:61130
decreased pre-B cell number J:61130, J:120460
increased B cell apoptosis J:131161
increased pro-B cell number J:61130, J:131161
spleen hypoplasia J:131161
Blnktm1Pjln/Blnktm1Pjln
involves: BALB/c
abnormal pre-B cell morphology J:58740
arrested B cell differentiation J:58740
decreased IgG3 level J:58740
decreased IgM level J:58740
decreased mature B cell number J:58740
enlarged spleen J:80332
increased mature B cell number J:157575
increased pre-B cell number J:58740, J:80332
increased tumor incidence J:80332

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory