Lmnb2 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Lmnb2
lamin B2
MGI:96796

18 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Lmnb1^tm1.1Sgy/Lmnb1^tm1.1Sgy Lmnb2^tm1.1Sgy/Lmnb2^tm1.1Sgy Tg(KRT14-cre)1Cgn/0 involves: 129P2/OlaHsd * C57BL/6 * DBA/2	abnormal keratinocyte morphology	J:174963
	normal integument phenotype	J:174963
	normal mortality/aging	J:174963
Lmnb1^tm1Yxz/Lmnb1^tm1Yxz Lmnb2^tm1Yxz/Lmnb2^tm1Yxz involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6	abnormal cell physiology	J:178993
	abnormal neuron differentiation	J:178993
	abnormal neuronal migration	J:178993
	abnormal neuronal precursor proliferation	J:178993
	abnormal phrenic nerve innervation pattern to diaphragm	J:178993
	abnormal pulmonary alveolus morphology	J:178993
	abnormal stratification in cerebral cortex	J:178993
	decreased embryo size	J:178993
	decreased fetal size	J:178993
	increased neuronal precursor cell number	J:178993
	microcephaly	J:178993
	neonatal lethality, complete penetrance	J:178993
	respiratory failure	J:178993
	thin cerebral cortex	J:178993
	thin diaphragm muscle	J:178993

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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